Categories: Uncategorized

Cabergoline / Cabgolin / Colette

Cabergoline

Category

Selective prolactin inhibitors

Dopamine receptor agonist

Ergot derivative 

Action

Reduce the amount of prolactin from pituitary gland

Indication

Induction oestrus

pseudopregnancy in bitches

induce abortion in queens and bitches

pituitary adenoma in rats

Dose

For pseudopregnancy@ 5mcg/kg PO for 5-10 days

For pregnancy termination @ 5mcg/kg PO for 5 days (at 30 days in cats and after 40 days in dog)

for oestrus detection @ 5mcg/kg PO OD induces fertile pro oestrus in 4-25 days and administer until onset of oestrus.

Contraindications

Cause abortion 

dopamine antagonist will counteract effect

 

Adverse Effects

anti hypertensive drugs will cause hypotension 

Availability

Cabgolin - Tab 0.25mg, 0.5mg

Colette - Tab 0.5mg

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