Prostaglandin F2α preparation

• Potent luteolytic agent
• It cause functional and morphological regression of the Corpus Luteum

• Drug of choice for endometritis in Cattle
• Anoestrus due to ovarian luteal cyst
• Silent / sub oestrus
• Termination of abnormal pregnancy (mummified foetus)
• Treatment of unwanted pregnancy
• Hydrops of foetal membranes
• Chronic endometritis / pyometra
• Induction of parturition
• Herd management
• Termination of pseudopregnancy
• Barren and maiden mares
• Synchronisation of oestrus

Cattle and Buffalo @

2ml (500mcg) - IM

Horses @

• Single IM Inj.  of 0.5-1 ml (mare have upto 400kg b.wt)
• 1-2 ml IM Inj (mare have more than 400kg b.wt)

Sheep and Goat @

0.5 ml (125 mcg) IM

Cat @

5 mcg/kg SC once daily for 3 days

Dog @

1-1.25 mcg/kg OD SC for 4-5 days 

• Pregnant animal (cause threatened abortion)
• Mare suffering from acute or subacute GI disorders and respiratory disease
• IV route is contraindicated

(Skin absorption is there, so take care during handling)

• Increased cardiac and respiratory rates
• Abdominal discomfort
• Watery diarrhoea
• Depression
• Vomiting and Nausea

(These signs are transient and last for 15-20 minutes)

Inj. PRAGMA (INTAS)

• 2 ml, 10 ml vials
• Each ml contain 250mcg

Inj. PREGOVA (VIRBAC)

• 2 ml vials
• Each ml contain 263 mcg

inj pg estro (HESTER)

• 2ml vials
• 250mcg/ml

Inj. ESTRUMATE

• 20 ml vials
• Each ml contain 250mcg

Inj. CLOSTENOL

• 2 ml vials
• Each ml contain 250mcg

Inj. ALPHA TWO

• 2 ml vials
• Each ml contain 250mcg