Anti emetic, pro kinetic
Central D2 receptor antagonism
5HT3 Antagonism - Higher dose
At Antiemetic chemoreceptor trigger zone.
GI prokinetic effect
-local D2 antagonism
-Stimulation of muscarinic Ach and 5HT4 receptors.
Vomiting, Desophagitis,Emptying stomach prior to induction of general anaesthesia.
Dog, cat - 1 to 2 mg/kg - (IV).
Birds-(0.3-2mg/kg) - IM
Pig - 0.5 - 1mg/ kg - (SC)
GI obstruction, perforation, epileptic patients,
Drug Interaction: Inhibited by Anti muscarinic drugs, and narcotic analgesics.
Tablets
Periorm-5,10mg
Injection
Perinorm-2 ml(5mg/ml).
Syrup
Perinorm- 30 ml ( 5mg/5ml).