Tranquilizers

• Dopaminergic antagonist (Bind to D1 and D2 receptors)
• Anti-emetic (Blockade of D2 receptors in CTZ and vomiting centre)
• Also bind to M1 and M2 and 5HT2B receptors)
• Also block Vagus nerve in GI tratct

• Pre-anaesthetic
• To increase tolerance of pain
• Failure of let-down milk
• Nausea & Vomiting
• Uterine and Vaginal prolapse

Ruminant @ 0.1mg/kg IV

Horse @ 0.2-0.3 mg/kg IV

Dog @ 1-2mg/kg IV or 2-4mg/kg IM 

Allergy

Blurred vision

Injection Siquil/Anicalm

• 5ml Vial
• Each ml contains 20mg Triflupromazine HCl