Antiprotozoal drug (Coccidiosis)
Vitamin B1 or structural analogue
Competitively block the thiamine transporter of Eimeria species
Control and treat coccidiosis in Calves, sheep, goat, puppies and birds
For Prophylaxis
Cattle @ 5mg/kg PO 21 days
For Treatment
Cattle @ 10 mg/kg PO for 5 days in feed or water
Cat @ 60-100 Total PO 7 days
Dog @ 100-200 mg in food PO 7 days
Poultry @ 0.012-0.24% PO in water for 3 days
Maximum Dose
Large animal 200 mg
Small animal 100 mg
Not used in puppies with 20 days of age
Excess dose in sheep cause encephalomalaciae
Calves - inhibit erythrocyte production
Toxicity at high dose
Amprolium powder 150g, 1kg
Amproforte (Amprolium fortified with vitamin) 100g, 1kg