Metronidazole / Metrogyl / Flagyl / meterkem METRONIDAZOLE CategoryAnti protozoa, antibiotics, Nitroimidazole.ActionNot known(Bacteria under anaerobic condition, binds to DNA - Cause death)-Interfere with pyruvate ferrodoxin reductase.-Interfere with enzyme in the bacteria's electron transfer system.IndicationGiardiasis, Intestinal problems,diarrhoea caused by protozoan,Treatment of other parasites(Trichomones,Balantidium coli)Treatment of anaerobic infection in horse Management of hepatic encephalopathy. DoseDog - 15 to 25 mg /kg for protozoan infection. (25mg/kg).Cat -8 to 10 mg /kg.Food animal prohibited. Equine- 20 to 25 mg /kg (BID).Elephant- 15 mg /kg rectally. Contraindications1st trimester of pregnancy. Toxic to king cobra.Toxic to small birds. Adverse EffectsVomiting, CNS Toxicity, Hepatotoxicity,hematuria.Drug Interaction:Phenobarbital, phenitoin may enhance, metabolism of metronidazole,Cimetidine may decrease the metabolism of metronidazole.Availabilityinj meterkem (ALKEM) - 100 ml (5mg/ml) Inj metrogyl -100 ml(0.5 mg /ml).Tablets:Metrogyl- 200mg , 400mg Flagyl - 200 mg ,400 mg .Susp:metrogyl - 30 ml, 60 ml(40mcg /ml).Flagyl - 60ml (40mcg per ml). DOSE CALCULATOR Related posts: Sodium Bicarbonate / pH 7.4 Piperazine hydrate / Ultraguard / Hartz Cetrimide / Lorexane / Scabimide / Tritix / Healex Erythromycin/ Althrocin / Anithrocin FS / Anithrocin SP / Erycin Propoxur / Big boss / Cisa Tix / Proxurr / Tickfree / Bolfo / Negasunt / Notix Iron + Vit B12 + Folic acid Methyl ergometrine / Methergin