Antibiotics (broad spectrum aminoglycoside) 

• Bactericidal
• Bind with 30s (stronger binded) & 50s subunit of ribosomes    a)  Interferes with formation of initiation complex of protein synthesis          OR       Inhibits protein synthesis

• Tropical preparations for skin, eyes, ears
• Oral treatment: Treatment of enteric infection and to sterile colon prior to surgery
• Orally/enema: To decrease NH3 producing bacteria in hepatic encephalopathy. 
• Antibacterial spectrum: G -ve aerobic, several G +ve     Resistance:  pseudomonas,  strepto Pyogenes

• Ruminants: 3-6 mg/kg   6-12 hours interval   PO  88 mg/kg   8 hrs interval   SC
• Horse: 2-6 mg /kg    6-12 hrs interval     PO                     4.4 mg/kg     8-12 hrs interval  IV
• Small animals: 10-20 mg/kg      6-12 hrs interval      PO

• Not safe in neonates
• Chronic use leads to superinfection
• Not safe in neuromuscular disorder, renal problems
• Horse: antibiotics associated diarrhea (enterocolitis) 

• Parentral: nephrotoxic
• Orally: ototoxicity, Nephrotoxicity, severe diarrhea, intestinal malabsorption

Spray aluspray - awd (VETOQUINOL) - 125 ml

• Inj. Neospa (140 mg/ml)   30 ml vial
• Inj. Omycin vet (140 mg/ml)   30 ml vial
• Pow. Nubiotic-SP (20% W/W)  - 50g                               Pow. Unimycin  50% - 20g
• Oint. Neosporin  5g, oint. Neosporin-H  5g, oint. Nebasulf 15g, oint vetbacin 20g