Antacids

Buffer mechanism of body

Severe metabolic acidosis

Cardiac arrest

Severe primary lactic acidosis

Severe diarrhoea

Alkalized urine

Adjuvant therapy for hypercalcemia/hyperkalemia induced crisis

Dog and Cat 

severe metabolic acidosis 8-12 mg/kg PO q 8hr

Goat and Cattle 

7.5% solution make it to 5% before IV

5% solution 5ml/kg

2/3rd 7.5% Sodium bicarbonate and 1/3rd NS

Hypocapnoeic patients 

Vomitting animals

Hypoventilating animals

Undesirable rise in plasma sodium concentration 

Hypernatremia

pH 7.4 injection 100ml 

Formulations 1.26%, 4.2%, 8.4%(pH 7.8) solution for slow IV