Acetaminophen / Capol / Poenophen / Rapidmol ACETAMINOPHEN CategoryNSAIDsPara-aminophenol derivative having analgesic and antipyretic properties ActionInhibition of Cyclo oxygenase (COX) enzyme More selectively for COX-2 than COX-1Anti-pyretic and analgesic effectIndicationOral analgesic in dogRelieve painFever reducerDoseDog @ 15 mg/kg POCalves @ 50 mg/kg PO followed by 30 mg/kg PO q6h ContraindicationsFatal for CAT (lack of Glucuronyl transferase enzyme that is responsible for metabolism of drug)In dog if renal or hepatic diseaseAdverse EffectsCan cause hepatic and renal toxicity Hb → methHb → SulfHb HaemolysisJaundiceAvailabilitySusp. Poenophen - 50 mg/ml (60 ml Bottle) - (MVDEX)Infusion Rapidmol - 1%w/v (100ml Sachet) IVSusp Calpol - 60mlTab Calpol - 500mg DOSE CALCULATOR