Vitamins

• Poor reproductive performance 
• irregular oestrus cycle 
• anoestrus
• poor conception rate

Cattle & buffalo @ 2.5-5ml IM

Inj AEI - 5ml vials (INTAS)

Urinary antiseptics

Methenamine does not have antibacterial properties in an alkaline environment (pH≥6); however, in a more acidic environment (pH<6), methenamine is hydrolyzed to formaldehyde. (1) Formaldehyde is considered to be highly bactericidal. (1) Formaldehyde has nonspecific antibacterial activity and works by denaturing proteins and nucleic acid of bacteria. (1) Certain bacteria such as Proteus sp. can alkalize urine, inhibiting the beneficial activity of formaldehyde. (1) The key role of the salt component of the drug, for example hippuric acid, is to maintain the acidic state of the urine. (1)

Urinary tract infection. 

Dog - 500 mg/ animal(BID)

Cat - 250mg.

Renal impairment, dehydration, metabolic Acidosis.

Tablet Mandelamine 500mg 

• Urinary alkanaliser
• Xanthine analogue
• Anti leishmanial drug

Decrease the production of uric acid by inhibiting enzymes responsible for uric acid synthesis

• Uric acid uroliths
• Leishmaniasis(administer with meglumine antimonite / sodium stibogluconate)

Horse @ 5 mg/kg PO

Dogs @

• For Uric acid urolith @ 10 mg/kg TID PO then reduce to 10 mg/kg OD PO
• For leishmaniasis @ 10 mg/kg BID PO for 4-6 months

BIRDs @ 10 mg/kg BID PO

NAD

Hypersensitivity

Tab 100mg, 300mg

Tab Aloric

Tab Ciprolic

Tab Zyrolic

Tranquilizers

• Dopaminergic antagonist (Bind to D1 and D2 receptors)
• Anti-emetic (Blockade of D2 receptors in CTZ and vomiting centre)
• Also bind to M1 and M2 and 5HT2B receptors)
• Also block Vagus nerve in GI tratct

• Pre-anaesthetic
• To increase tolerance of pain
• Failure of let-down milk
• Nausea & Vomiting
• Uterine and Vaginal prolapse

Ruminant @ 0.1mg/kg IV

Horse @ 0.2-0.3 mg/kg IV

Dog @ 1-2mg/kg IV or 2-4mg/kg IM 

Allergy

Blurred vision

Injection Siquil/Anicalm

• 5ml Vial
• Each ml contains 20mg Triflupromazine HCl

Thyroid drug

T4 and T3 bind to thyroid receptor protein in the cell nucleus and cause metabolic effects through the control of DNA transcription and protein synthesis

Hypothyroidism

Cat @ 0.05-1mg per cat

dig @ 0.02 mg/kg PO BID for 4-8weeks

If serum TSH level is already suppressed

Patient with underlying cardiovascular disease

Risk of precipitating overt thyrotoxicosis.

Tab eltroxin 50mg, 100mcg

Tab thyronorm 25mcg, 50mcg

Thyroid drug

Decrease the uptake and concentration of inorganic iodine by thyroid

reduce the formation of di-iodotyrosine and thyroxine

(converted into methimazole after absorption)

Anti thyroid

Feline hyperthyroidism 

Neonatal thyrotoxicosis

graves’ disease

diffuse toxic goitre

Cat @ 5mg tabBID PO daily 2-3 weeks per cat

Hyperthyroidism due to nodular goitre and liver disease

Teratogenic effects

Thyrocab - Tab 5mg, 10mg, 20mg

• To treat Mastitis (subclinical mastitis)
• Adjunct to antibiotic therapy in clinical mastitis

Milk pH buffer - Act as milk pH buffer and normalize the  milk pH from alkaline to normal i.e., 6.5. This makes the milk unfavourable for microbial growth and free from bacterial contamination.

Immunopotentiator - Mammidium improves the cellular immunity against mastitis, therapy protects mastitis affected tissues

Antioxidant effect - Mammidium enhances cellular antioxidant level, which reduces cellular oxidation and prevents mastitis

• Sub-clinical mastitis
• Adjunct to antibiotic therapy in clinical mastitis

50 g powder for 4 consecutive days as an Electuary by mixing with jaggery

NA

NA

Amber coloured glass bottle containing 50 g powder

Synthetic polycyclic steroids

• Preferential inhibition of 5-alpha-reductase (Type II) enzyme
• This enzyme converts testosterone into dihydrotestosterone that cause enlargement of prostate

Benign prostatic hypertrophy

Reduce prostate size without affecting semen quality and testosterone production 

Dog-0. 1-0.5 mg/kg OD PO  

Used only in males not female

In breeding animals, it can get secreted into semen, can cause fetal abnormalities.

Tablet finalo (1mg) 

Tablet fincar (5mg) 

Sedative

Alpha-2 adreno receptor agonist

Sedative , analgesic, muscle relaxant, blood pressure maintenance.

Cattle-22to 50 µg/ KG
Pig - 80 micro gram per Kg

dog -

1.pre-Anastasia 10 to   20 micro gram per KG

2.slight session 10 to 30 micro gram per KG

3.moderate to dip station 30 to 80 micro gram per KG

cat-

1.moderate sedation- 50-100 µg/ KG,

2 Deep sedation 100 - 1 50 µg/ KG.

Pregnancy animal

Pregnancy toxaemia

Domitor(1mg/ml) —10ml

Livmedet(40mg/ml)—20ml

Sedative

Inhibitory neurotransmitter in CNS

• Muscle relaxant
• Control of seizure
• Anaesthetic

• Ruminant=0.6-1.1 mg/kg
• Horse - 0.05-2mg/kg IV 

Dog=preanesthetic - 0.2-0.5mg/kg IV.

•  Muscle relaxant -2-10 mg/kg PO.                                         

Seizure management - 0.5-1 mg/kg IV     

Cat=Anxiolytic:0.2-0.4 mg/kg PO.                                   

• Appetite stimulant : 0.5-1 mg/kg IV.                                     
• Muscle relaxant : 1.25-5 mg/kg PO

• Thrombophlebitis
• CNS excitement in drugs

Depression in cats

• Tab. Valium 5mg,10mg
• Injection Dizapam 2ml
• Tab Calmpose 2mg, 5mg, 10mg
• Inj Calmpose 2ml (5mg/ml)