Bronchodilator

Inhibition of phosphodiesterase (PPE 1 & PPE 2)enzymes

• CHF
• Bronchitis
• Emphysema
• COPD

• Dog=6-10mg/kg I/V or PO
• Cat=4-6mg/kg I/V or PO

• Pregnancy hypocalcaemia
• Hepatic disorder

• Nausea
• Vomiting
• Headache

Deriphyllin  - 2ml

Bronchodilators 

Potent inhibitors of phosphorus enzyme and increase cAMP

Feline bronchial asthma

Cats @ 6.6mg/kg PO BID and 2-4mg/kg slow IV

dogs @ 9-11mg/kg TID/qid

NA

Excitement and hypocalcaemia

Tab 100mg

Inj 250mg/10ml

Fluoroquinolone

Inhibits supercoiling of DNA in the bacteria, producing bactricidal action.

Respiratory tract and urinary tract infection in cats and dogs

Glasser’s disease in horse

Infectious Cory a, colisepticemia, CRD, salmonellosis, fowl cholera

Cat & dog @ 5-15mg/kg PO IM IV

Cattle & sheep @ 4-5mg/kg PO IV IM

In Young ones cause arthropathic effects

GI disturbances 

CNS disturbances and rashes

C-flox TZ - Bol 3.3gm and Tab 550mg (Dose @ Large animals 1-2 Bol OD for 3-5 days and in small animal 1tab/15-25 kg bw) (INTAS)

INJ. C-flex TZ IU - 60ml bottle (125mg Ciprofloxacin + 150mg tinidazole / 5ml) (INTAS)

Ceflox-Tz vet - Bol 3.3G and Susp 60ml 

Ciptas -L - Tab 250 mg ((In small animal 0.5-1 tab /20-25 kg bw BID for 3-4 days)

Griptol - Susp 60ml (In small animal 5ml/20-25kg BW BID for 3-4 days)

Antibiotics

A bacteriostatic Macrolides antibiotic binds to 50s ribosomal subunit suppressing bacterial protein synthesis

Against mycoplasma

Dogs -10 to20 mg/kg PO q 12 hrs,

cattle - 18 mg/kg IM q 24 hrs,

Goat - 10 mg/kg (do not exceed more than 5 days) ,

Birds - upper respiratory tract infection 10 -40 mg/kg IM, BID Or TID ,

elephant - 12 mg/kg OD for 5 days ( Mycoplasama infection)       

POWDER FORM                        Dogs- 1/16 th of teaspoon 2-3 times daily for dogs less than 7 kg, (greater than 7 - 15kg ) - 1/8 th of teaspoon  2-3 times a dog for medium dogs 1/4 teaspoon 2-3 times a day for larger dogs( greater than 15 kg) 

Don not give to guinea pigs, hamster, rabbits

• Gastro intestinal upset         pain and inflammation at injection site                             decreased appetite, diarrhoea

Trox powder (VIRBAC) - 120g (50%w/w)

powder TYLO 62.5,100g       

inj. Tylan 200,250ml

Macrolytic antibiotic
prokaryotic drug

Bind to 50s sub unit of bacterial ribosome and prevent growth of bacteria by interfering with protein synthesis

Only in foal below 1 year not above Respiratory tract infection
Genital tract
Skin and soft tissue
Against intracellular organism

Cattle @
As prokinetic @ 1.1 to 8.8 mg/kg IV Single dose in leucocytes

Cat @ 5mg/kg PO Once daily

Dog @ 5-10(upto 40)mg/kg PO Once daily

Foals @ 10 mg/kg PO Once daily (initially) followed by alternate days

Hypersensitive patient
Liver disfunction
Horse above 1 year fetal digestive disturbance

G.I disturbance
Very rarely nervousness dermatological reactions

Inj Azee 500mg (Each ml of reconstituted injection contains 100 mg)

Suspension Azee 100mg/ml

Tab Azee 250mg, 500mg, 1000 mg

Powder Azithral P 100g, 1000g

Marcrolid antibiotics

Like other macrolid antibiotics bind with 50s ribosomal subunit and cessation of bacterial protein synthesis

Cat @ 10-15 g/kg PO

dog @ 10-40g/kg PO

cattle, sheep, goat,horse @ 2.2-4.4 g/kg bw PO

Allergies from other macrolids like Azithromicin

• do not combine with digoxin

Nausea, vomiting, diarrhoea, stomach pain, loss of appetite

Althrocin - Tab 250 and 500mg and Liq 60 ml (125g/5ml)

Anithrocin FS. - Powder 1g

Erycin - Tab 125 mg, 250 mg, 500mg

Antibiotic

It inhibit the bacterial proteins synthesis

Gram-positive cocci

Obligate anaerobe

Cat & dog @ 22mg/kg IM q12h hrs parenteral

11mg/kg slow IV

Rapid IV should be avoided

Rapid IV can result in collapse due to cardiac depression

Inj lincovet 5ml and 30ml (300mg/ml)

Antibiotics

Inhibit bacterial synthesis of dihydrofolic acid

Soft tissue infection

coccidia

Pneumonia

Urinary tract infection

Dog and cat 100mg/kg PO IM or 50mg/kg BID PO

Cattle 220mg/kg PO, IM following 110mg/kg OD PO IM

sensitive animals

Blood dyscrasias

Anaphylaxis

Stevens-Johnson Syndrome

Bilsulpha 100ml

Bol. Sulphadimidine

Bol. Pabadine 5g

Fluroqunolones Antibiotics.(Eye, ear Antibiotics).

Inhibits bacterial DNA gyrase enzyme. 

Bactericidal.

Staphylococcus spp,Pseudomonas aerugenosis,Bacterial conjunctivitis,Bacterial infection of eye,corneal ulcer, skin infection, pneumonia.

Dog-10 mg/kg

Horse-5.8mg/kg.

<6months of age

CNS toxicity, especially in animals with renal failure

Opthocare M eye drops - 5ml.

Moxiflox eye drops-5ml,

Bromiflox eye drops -5ml,

Moxiflox P eye drops-5 ml,

Ointment: Moxiflox 0.5 %.

Inj:Mofoi [100mg/kg]  25 ml, 100ml vial