Antiseptic

Slowly releases oxygen and acts as antiseptics

Have keratinolytic and antiseborrheic activity

Pyoderma in dogs

Topical treatment or bacterial skin infection dogs

Systemic antimicrobial 

2-3 times weekly

Excessive dryness of skin, erythema, odema, transient stringing or burning sensation

Pet ben -Topical 2.5% Shampoo 

ADI cure 2.5 gel

Brevoxyl cream

Persol gel

Benzac AC GEL

Antiprotazoal drug

Aminoglycoside that acts against Gram -ve, Gram+ve, cestodes, and protozoans, Impairs protein synthesis Leishmanicidal action, inhibitior of parasite, 

Leishmaniasis, cryptosporidiosis, giardiasis

Dogs- 150 mg/kg B. Wt for 5 days 

Cats - not recommended

Calves- 100 mg/kg B. Wt for 11 days 

Hypersensitivity, intestinal obstruction, GI ulceration, Nephrotoxicity, pancreatitis

Inappetance, Diarrhoea, Nausea, Vomition

Paronomycin sulfate capsule 50 mg

Anti protozoal

• Trypanostatic 
• It causes a kinetoplastic D.N.A. condensation.
•  It causes the loss of ribosomes with possible aggregate formation with large
  number of lysosomes.

•  Prevention and treatment of Trypanosomiasis
• Prophylaxis in horse

• Dissolve Antrycide ProSalt 2.5 g in 15 ml. of water for injection and inject @2 ml per 45 kg body weight by subcutaneous route Antrycide is administered by subcutaneous route.
• In cattle, the common sites are behind the shoulder, the midline of the dewlap or the caudal fold.
• The dose may be divided between several sites, and these should be massaged following injection.

• Only SC route

• Local irritation at site
• In horses, salivation, sweating and tremors may occur

Antricide Pro Salt

• 2.5 gm vial
• One vial containing:
  Quinapyramine Sulphate B.Vet.C. – 1.5 g
  Quinapyramine Chloride B.Vet.C – 1.0 g
  One Ampoule of sterile water for injection IP – 15ml

Inj Triquin ( VETOQUINOL)

• 2.5 g vials
• One vial containing:
  Quinapyramine Sulphate – 1.5 g
  Quinapyramine Chloride - 1.0 g

Inj Triquin s ( VETOQUINOL)

• 2 g vials
• One vial containing:
  Quinapyramine Sulphate – 2gm

Antiprotozoal 

Exact mechanism not known

It is medication used to prevent and treat malaria in area where Malaria remains sensitive to chloroquine

Autoimmune disease

Discoid lupus erythematous in dogs

Dog- 5mg/kg orally, OD with tacrolimus ointment

Overdose- drowsiness, visual disturbance, CV collapse, convullsion, HYPOKALEMIA

High dosage causes drowsiness

IMULAST tablet 200mg

HCQS tablet 200mg

QDMRD tab 200mg

RHQ tab 200 mg

Antiprotozoal (carbanilide diamidines) 

• Not clear
• Combining with protozoal DNA causing DNA to unwind and denature & interferes with DNA synthesis

• Antiprotozoal spectrum: babesia, cytauxzoon, hepatozoon, anaplasma, Ehrlichia.       Babesia (canis, gibsoni, caballi) 
• Intracellular tick borne pathogens
• Babesiosis, anaplasmosis, Ehrlichiosis, cytauxzoon folis infection

In cats not used

Horse @ 2.4 mg/kg IM

Cattle & Buffalo @ 3-4mg/kg IM

Dog @ 6.6mg/kg IM SC Once (Repeat in 2-3weeks)

• Low therapeutic index
• Mild cholinergic signs
• Anaphylaxis
• Pain at injection site
• Hepatic and renal impairment

Inj. Imizet (INTAS)

• 5 ml and 10ml vials
• 120mg/ml

Anti protozoal

Enters RBCs and inhibit parasitic cell and digestive vacuoles by simple diffusion 

Malaria

Avian malaria - 5mg/kg 6, 18, 24 hrs

NA

Na

Lariago - Tab 250, 500mg 

Syrup - 60ml (160mg/10ml)

Inj 5ml (64.5mg/ml)

Lincosamide antibiotic 

Inhibit protein synthesis by reversible binding to 50s ribosomal subunit, blocking the transpeptidation

Pyoderma, Toxoplasmosis, Bone and joint infection

Cat & dog @ 5.5mg/kg BID 

For toxoplasmosis in cat & dog @ 25mg/kg OD in divided dose

Rabbit, chinchillas, hamsters

In hypersensitive animals

Clivet - Solution 20ml (25mg/ml), Inj 2ml and Tab 150mg and 300mg 

Goclin - Tab 150mg and 300mg

Bioclan - Syrup 25mg/ml

Dalacin C - Inj 300mg/2ml

Clindapet - Tab 150mg and 300mg

Dalcap - Capsules 150 mg

Dalcinex - Caps 150 mg and 300 mg

Anti protozoa, antibiotics, Nitroimidazole.

Not known

(Bacteria under anaerobic condition, binds to DNA - Cause death)

-Interfere with pyruvate ferrodoxin reductase.

-Interfere with enzyme in the bacteria's electron transfer system.

Giardiasis, Intestinal problems,diarrhoea caused by protozoan,

Treatment of other parasites(Trichomones,Balantidium coli)

Treatment of anaerobic infection in horse 

Management of hepatic encephalopathy. 

Dog - 15 to 25 mg /kg for protozoan infection. (25mg/kg).

Cat -8  to 10 mg /kg.

Food animal prohibited. 

Equine- 20 to 25 mg /kg (BID).

Elephant- 15 mg /kg rectally.

1st trimester of pregnancy. 

Toxic to king cobra.

Toxic to small birds.

Vomiting, CNS Toxicity, Hepatotoxicity,hematuria.

Drug Interaction:

Phenobarbital, phenitoin may enhance, metabolism of metronidazole,

Cimetidine may decrease the metabolism of metronidazole.

inj meterkem (ALKEM) - 100 ml (5mg/ml) 

Inj metrogyl -100 ml(0.5 mg /ml).

Tablets:

Metrogyl- 200mg , 400mg 

Flagyl - 200 mg ,400 mg .

Susp:

metrogyl - 30 ml, 60 ml(40mcg /ml).

Flagyl - 60ml (40mcg per ml).

Antibiotic

• Bacteriostatic
• Inhibit protein synthesis

Tickborne disease (DOC)

Dog:

• Anaplasmosis= 5-10mg/kg PO q 12hr 7-10 days
• Toxoplasma gondii= 5-10mg/kg for 4 weeks
• General infection= 3.5mg/kg PO q 12hrs 7-14 days

Ruminant= 20mg/kg

Hypersensitive patient

• Decrease appetite
• Difficulty in swallowing
• Feel discomfort

• Doxicip-100- 100 capsule
• WELLDOX-100   100mg
• Dr Doxy 300 mg
• Doxy Must Tab 300 mg
• Doxicip Tab 100mg and 200mg

Antibiotics

Inhibits bacterial protein synthesis

bacteriostatic, broad spectrum antibiotics, rickettsial , spirocheter mycoplasma and other microbes

• Cattle = normal dope = 5-10 mg/ kg IM OD 2.5-5mg/kg IV OD 
• Anaplasma 20mg/kg for control or prevention every 21-28 days IM
• For eliminating coma state 22mg/kg IM or IV for 5 days
• Theileria 20mg/kg IV or IM for 10 days 
• Sheep/Goat - 6-11 mg/kg IV or IM
• Horse 6.6-10 mg/kg slow IV
• Dog - 7.5-10 mg/kg IV, BD 10-20mg/kg PO , BD
• Cats - mycoplasma 10-25 mg / kg IV , TID for 5-7 days  .Heamobartonelcosis - 16-20mg/kg PO, TID
• Birds controlling outbreak -200mg/kg IM OD 3-5 days .   Psittacosis 50mg/kg IM OD, 3-5 days 

Hypersensitivity reford fetel skeletal development, Hepatotoxicity , teratogenic effect (2nd half of pregnancy)

• Rapid IV can cause cardiac arrhythmias and transient collapse due to chelation of intravascular ca2+ ions
• Oral tetracycline should not be given to the Cats cause fever, hair loss,colic vomiting, diarrhoea, hypotension

vetocyclin ds ( VETOQUINOL)

• Inj 30ml and 100 ml vials
• 100mg/ml

oxetetracycline hydrochloride injection ip vet ( VETOQUINOL)

• Inj 100 ml vials
• 50mg/ml

Avoxin

• Inj 100ml
• Each ml contains 50mg

Avoxin LA

• Inj 50 ml
• Each ml contains 200 mg

Oxyney 

• Inj 100ml
• Each ml contains 50mg

Bixy DS

• 30 ml, 100ml vial
• (100mg/ml)

Bioxy LA

• 30 ml
• Each ml contains 200 mg

V cycline

• Powder 30%
• 100g , 500g

 Terramycin

• Powder 30g
• Inj 20 ml, 200 ml, 500 ml
• Each ml contains 200 mg

Oxytetracyclin Tab. 500mg

• Steclin
• 30ml, 50ml, 100ml
• Each ml contains 50mg