Anti Protozoal

Block the parasite respiratory chain

Used for therapy and  Prophylaxis of all forms of theileriosis

Have antileshmanial activity

2.5 mg /Kg IM single dose

Strictlya as Deep IM injection

Inj Zubion (INTAS)

• 2ml, 20ml and 30ml vials
• 50mg/ml

Inj Zubion f (INTAS)

• 30ml vials
• Each ml contains 50mg buparvaquone + 55 mg furosemide 

Butalex 50mg/ml

Boviquone

Prozoff

vetbuparva

Anti protozoal 

It inhibits DNA synthesis by interfere with aerobic glycolysis 

Trypanosomiasis, babesiosis, Cytauxzoonosis

• Dog:-
• For Babesia= 3.5-5 mg/kg I/M (B. canis)

3.5-5mg/kg I/M 24 hrs (B. gibsoni)

• For Trypanosomiasis= 3.5-7 mg/kg I/M 2 weeks
• Ruminants = 3.5mg/kg I/M

Vomiting and diarrhoea in dogs

• Tachycardia
• Nystagmus
• Opisthotonos

Inj nilbery (INTAS)

• 30 ml and 90 ml vials
• Each ml contains 70mg diminazine aceturate + 375mg phenazone

Inj Prozomin (VIRBAC)

• 30ml, 100ml vials
• Each ml contains 70mg diminazine aceturate + 375mg phenazone

• Injection Berenil Vet 7% 20ml,30ml,90ml
• Injection Batrynil 30ml,90ml
• Inj Demin 100ml

Anti cancer ( Vinca alkaloid group)

• Inhibition of microtubule formation in mitotic spindle, resulting in an arrest of dividing cells at the metaphase stage
• For thrombocytopenia, increase thrombopoiesis, increase fragmentation of megakaryocytes, decrease platelet destruction and decrease destruction of platelets by macrophages

• Transmissible venereal tumor (TVT) in dogs
• Mammary neoplasia in cats
• Lymphoreticular tumors
• Rhabdomyosarcoma

(Use gloves while administering drug)

Dogs and Cats@

Antitumor

0.025-0.05 mg/kg IV (once/week)

Thrombocytopenia

0.02 mg/kg IV (once/week) with prednisolone

• Teratogenic and embryo toxicity in pregnant animal
• IV route only
• Fatal Intrathecally (if given, immediate removal of spinal fluids and flush with RL as well as other fluids)

• Neuropathy
• Constipation
• Irritating to tissue (Avoid extravasation outside the vein)

Inj Vinlon 1

• 1ml vial
• Each ml contains 1 mg

Inj Cytocristin

• 1ml vial
• Each ml contains 1 mg

Beta blockers (Anti-hypertensive)

Effective by reducing total peripheral resistance and vast dilation, by blocking alpha adreno receptor

Chronic heart failure

Dog

Initial dose - 0.1-0.2 mg/kg BID

Target dose 0.4mg/kg BID

Supraventricular bradycardia

Av block

Avute heart failure

Carca

Tab 3.125, 6.25 and 12.5 mg

Cevas

Tab 3.125 and 12.5 mg

Antihistamine

Responsible for a wide variety of allergic symptoms rich as puritis, rhinorrhea and watery eyes 

Hydroxyzine is a potent inverse agonist of histamine H1 receptor. They not only block the completely stop activity of lutamine receptors 

Inverse agonism increase the hydroxyzine deficiency

Antipruritic, Antihistamines

Flea allergy dermatitis

Dog- Antipruritic/flea allergy- 2.2mg/kg 

Cats- Antipruritic - 1-2mg/kg

Horse- 0.5- 1mg/kg BID

Birds- Allergies- 1 to 2 mg in 120 ml water /2mg/kg TID

Dry mouth, decrease GI secretion

Some teratogenic effects

Tablet Atarax 10mg, 25 mg

Atarax syrup 100ml (10mg/50ml) 

Atarax drop 15ml(6mg/ml) 

Injection Atarax 2ml (25mg/ml) 

Antihistamine

Seratonin antagonist, Calcium channel blocker

It bind and block the H1 histamine and serotonin receptors

Inappetance

Allergy

Cat and dog @ 0.1-0.5 mg/kg BID /TID

Use carefully in urinary retention and pyloroduodenal obstruction. 

Ciplactin

Tab 2 mg and 4mg, Syrup 100 ml (2mg/5ml)

Practin

Tab 4 mg and Syrup 100 ml (2mg/5ml)

Antihistamine, local anesthetic

Act by preventing the binding of histamine to HI receptor 

Antihistaminic, can be allergic , anaphylactic reactions

Dog/cat-0.2-0.4 mg/ kg I/M, 5.25-12 mg/kg PO

Mild sedation or reduced seizure threshold

Convulsions, high fever, muscle stiffness

Phenergan 

• 2 ml ampoule
• Each ml contains 25 mg

Avomine

• Tab 25 mg

Anti histamine 

Block H1 receptor

Allergic reaction 

Prurirtis

Cattle @ 30-50mg total dose

cats @ 2mg/cat q12h PO

dogs @ 4-8mg/dog q12h PO (0.5mg/kg maximum dose q12h)

Glaucoma 

ileus

cardiac arrhythmia 

Don’t use in glaucoma, cardiac arrhythmias and ileus

Inj Anistamin (INTAS)

• 100 ml vials
• (10mg/ml)

Cadistin - Tab 4mg and Inj 30ml , 100 vial (10mg/ml)

Chlorazin - Inj 100ml (10mg/ml)

Chloril - 30ml and 100ml (10mg/ml)

Anti histamine

Pheniramine acts as an antagonist to allergic symptoms stemming from inappropriate histamine release to reduce edema, itching, and redness

Itching of unknown genesis and of various localization, eczema, dermatitis, urticaria, skin oedema, insect bites, photodermatitis, rhinitis, tail eczema in horses, stomatitis, toxic hoof corns and inflammation of the hooves of cattle, paresis during pregnancy, puerperal toxemia and secondary retention, pulmonary oedema in cattle, pulmonary emphysema in horses, toxic hypopepsia.

IM / IV

Large animals: 5-10 ml or more

Small animals: ½ -1 ml or more

Injection may be repeated after 8-12 hours, if necessary.

Allergy 

Lethargy, vomiting and diarrhoea 

Inj Avilin Vet

• 10 ml, 33 ml vials
• Each ml contains 22.75 mg

Inj Alert Vet

• 10 ml, 30 ml vials
• Each ml contains 22.75 mg

Inj ALG Vet

• 30 ml, 100ml vials
• Each ml contains 22.75 mg 

Inj Hisloc

• 100 ml, 30 ml vials
• Each ml contains 22.75 mg

Inj Histal

• 10 ml, 30 ml vials
• Each ml contains 22.75 mg

Inj Pheniramine maleate

• 30 ml vials
• Each ml contains 22.75 mg

Antihelmintic drug

Affect Cl-channel of CNS of arthropod

• Endo and ectoparasiticide
• GI infection
• Lungworm
• Lice
• Mange

Cat = 0.6mg/kg S/C weekly once

Dog= 0.6mg/kg S/C weekly once for 4 week

Cattle= 0.2mg/kg S/C or I/M

Nil

• Oedema
• Pruritis 

• Doramcare 1%
• Duromect 1%
• Inj Dectomax 100 ml (10mg/ml)