• Analgesics
• Antispasmodics

Block the synthesis of prostaglandin in CNS

Release Beta-endorphin

•  Pain in colic and other spastic conditions of the abdominal organs
•  Acute and chronic arthritis
• Rheumatic conditions of muscles and joints
• Neuritis
• Neuralgia
• Obstruction of the oesophagus by foreign bodies-to relieve spam.
• In gastritis of small domestic animals to prevent vomiting.

ROUTE - IM (SC is contraindicated)

Cattle @  8 ml per 100 kg body weight 

Horses @ 20-60 ml 

Calves @ 5-15 ml

Sheep and Goats @ 2-8 ml 

Dogs @ 1-5 ml

• Do not use in cats.
• Do not use by subcutaneous route.
• Vetalgin should not be used in animals with disturbance of haemotopoietic system

• Long term use - Agranulocytosis
• Overdose - Convulsive seizure
• Neutropenia
• Analgin + Chlorpromazine - severe hypothermia

Injection Vetalgin® Vet

• 33m vial
• Each ml contains

Analgin I.P. ..... 0.5 gm and Chorobutol I.P. ......0.4 % w/v

• Analgesics-Antipyretics-Anti-inflammatory-Antispasmodics

NA

• Musculoskeletal Pain
• Lameness & Arthritis
• Post-Operative Pain
• Abdominal Pain 
• Fever

Large ruminants @ 4ml/100kg b.wt IM only

Small ruminants @ 1ml/100kg b.wt IM only

NA

NA

Injection Rumilide

• 30ml, 100ml vial

• Each ml contains NIMESULIDE 100 mg , PITOFENONE 2 mg, FENPIVERINIUM BROMIDE 0.02 mg

Analgesics
Antispasmodics

Block the synthesis of prostaglandin in CNS

Release Beta-endorphin

• Pain in colic and other spastic conditions of the abdominal organs
• Acute and chronic arthritis
• Rheumatic conditions of muscles and joints
• Neuritis
• Neuralgia
• Obstruction of the oesophagus by foreign bodies-to relieve spam.
• In gastritis of small domestic animals to prevent vomiting.

ROUTE - IM (SC is contraindicated)

Cattle @  8 ml per 100 kg body weight 

Horses @ 20-60 ml 

Calves @ 5-15 ml

Sheep and Goats @ 2-8 ml 

Dogs @ 1-5 ml

Do not use in cats.
Do not use by subcutaneous route.
Vetalgin should not be used in animals with disturbance of haemotopoietic system

Long term use - Agranulocytosis
Overdose - Convulsive seizure
Neutropenia
Analgin + Chlorpromazine - severe hypothermia

Injection Vetalgin® Vet

33m vial
Each ml contains

Analgin I.P. ..... 0.5 gm and Chorobutol I.P. ......0.4 % w/v

NSAID

Non selective cox inhibitor 

Used in pain and inflammation management in osteoarthritis condition

Dog- 15-22 mg/kg for 8-12 hr 

Cat - not used

Cattle-4-8mg/kg for 24 hr

Horse-4. 4-8.8mg/kg po 3-6mg /kg Iv

Elephant-3mg /kg po for 48 hrs or 2-4 mg/kg rectally

Cl in dehydrated, hypovolumic /hypersensitive patients, do not give to pregnant animals and aged animals

Diarrhoea, skin rashes

Injection- Artisone S 100 mL, Esgipyrin N 5 ml amp

Non steroidal Anti inflammatory drug

• Tolfenamic Acid has produced analgesic and anti-inflammatory effects by inhibiting the
  synthesis of prostaglandins.
• The enzyme inhibited by NSAIDs is the cyclooxygenase enzyme (COX).
• Tolfenamic Acid is a balanced COX-1/COX-2 inhibitor.

• All painful inflammatory conditions associated with Musculoskeletal Disorders, Respiratory Tract Infections, Mammary Gland Infections, Urogenital Tract Infections and Postoperative care
• Gel for Laminitis, Arthritis, Mastitis, Myositis, Bursitis, Sprains, Tenosynovitis/Tendinitis

Cattle and Buffalo: by IV/ IM Route: 4 mg/kg b.wt. as a single
dose or 2 mg/kg b.wt. to be repeated after 48 hrs.

Sheep and Goat: By IM or IV Route: 2mg/kg b.wt. as a single dose.

Pig: By /M Route: 2mg/kg
b.wt. as a single dose.

Horse: By IV Route: 2mg/kg b.wt as a single dose.

Dog- 4 mg/kg IM, SC repeated once after 24 hrs for 3 days                  

Cats -4 mg/kg SC repeated after 24 hrs PO for 3 days     cattle-2 mg/kg IM 48 hrs interval                               

• Animals prone to GI ulcers
• Do not administer with other ulcerogenic drugs such as corticosteroids.
• Not use in pregnancy

• Vomiting
• Diarrhoea

Bolus MAXXTOL - 500 (INTAS)

Inj. MAXXTOL - 30ml, 100ml  (40mg/ml) (INTAS)                       

Inj. MAXXTOL XP  - 20ml, 100ml   (80mg/ml)   (INTAS)

Gel - Maxxtol Top gel - 30 gm tube (INTAS)

Inj. Tolfine (VETOQUINOL)- Inj 30ml and 100 ml vials ( 4% and 8% available )

                       
Bolus. Tolfine (VETOQUINOL )- 500  mg

inj aletol (ALEMBIC) - 20ml vials (80mg/ml)

Top Gel Maxxtol - 30 gm tube 

• NSAIDs

• Pain
• Fever
• Pyrexia
• Musculoskeletal affections
• Lameness
• Postoperative therapy
• Uterine Prolapse
• Broncho-pneumonia
• Mastitis

Large animal @ 2 bolus BID

Small animal @ 1 bolus daily

Bolus pyridase

Each bolus contains

• Nimesulide B.P. 400mg
• Paracetamol I.P. 1500 mg
• Serratiopeptidase I.P. 75 mg

Bolus Bolin-NP (VETOQUINOL)

Each bolus contains

• Nimesulide B.P. 400mg
• Paracetamol I.P. 1500 mg

bolus serakind plus (VETMANKIND) - 60 mg serratiopeptidase

• NSAIDS

cyclooxygenase 2 inhibitor

• Osteoarthritis
• Myositis
• Bursitis
• Tenosynovitis
• Pyrexia
• Fever
• Inflammatory conditions
• Painful condition

Large animal @ 2-4 mg/kg b.wt

Small animal @ 0.5ml/ 10 kg b.wt

This drug must be used with caution in animals with liver and kidney dysfunction.

In addition, nimesulide has a range of other anti-inflammatory effects, including inhibition of the neutrophil oxidative response and inhibition of platelet activating factor

Oxalgin N P Injection

• 15ml, 30ml
• Each ml contains 100mg

Bol Bolin N P

• Management  of Pyrexia & Pain in cattle, buffaloes, sheep & goat. Supportive in Ephemeral fever.
• 2 boli twice daily

NSAIDS

Inhibits COX-2  enzymes 

Limits production of prostaglandins.

Post-operative pain 

Reduce inflammation

Reduce pain

Cattle @ 0. 5 mg per KG(IV ,IM)

• 1ml/10 kg kg bwt in mastitis, pneumonia, uterine prolapse and surgical interventions
• 1ml/25 kg bwt for musculoskeletal disorders, otitis, FMD and inflammatory conditions

Sheep and goat @ 1mg /kg (IV ,IM).

Horse @ 0.6 MG per kg bwt.

Dog @ 0.2 to 0.3 mg per kg bwt

Cat @ -0.2 MG per kg bwt.

Dehydration, hypovolaemic pressure hypo intensive patients,Late gestation,less than six week age.

Ulcer

Inj Melonex (INTAS)

• 15ml, 30ml and 100ml vials
• Each ml contains 5 mg

Bolus Melonex (INTAS)

• Each bolus contains 100 mg
• Large animals @ 2 bolus/400 kg bwt daily
• Small animals @ 1/4-1/2 bolus daily orally

Inj Melonex Power (INTAS)

• 30ml, 100ml vials
• Each ml contains 20 mg meloxicam + 1% w/v lignocaine

Melobest

Melobest P

NSAIDs

• Inhibit CoX-1 and CoX -2 So producing less amount of Prostaglandin. 
• Antipyretic, anti-inflamatory and analgesic effect. 

Relieve pain, tenderness, swelling and stiffness. 

Dog- 2mg/kg  IV, SC, IM,OD.

        1mg/kg  PO, OD

Cat -2mg/kg SC

          1mg/kg PO

• Hypovolemic/Hypotensive patients. 
• Dehydrated animals. 
• Cats show adverse effects 

• Vomiting
• Diarrhea
• Inappetence,
• GI Ulceration,
• Mild liver inflammation. 

Inj. Neoprofen

• 1% w/v
• 15 ml, 100 ml vial

Inj. Vetprofen

• 1% w/v
• 15 ml vial

Inj. Ketofen

• 100 ml vial
• 100 mg/ml

Inj. Profen

• 100 ml vial
• 100 mg/ml

NSAIDs

Cox Inhibitors

Anterior uveitis

Ulceration keratitis (when topical corticosteroids are contraindicated)

Cat & dog @ 1drop per eye at 6-24hr interval

As an analgesics @ 0.25mg/kg IM BID/TID in cats and 0.3-0.5 mg/kg IV IM BID/TID in dog

Renal disease

• This may cause the eye to sting for a short period after application
• This can affect and delay wound healing
• This can affect platelets causing an inability to clot blood
• This can cause local irritation resulting in redness and irritation of the tissues surrounding the eye

Ketodrops LS 5ml

Tab kelac 10mg

Inj ketorol 1ml (30mg/ml)