Opoid analgesic

Partial agonist at mu opoid receptor

Full agonist at ORC 1 - nociception and opoid receptor

Competitive antagonist at K opoid receptor

Analgesia

CNS depression, sedation, Emetic centre

Cough centre - Antitussive

Respiratory depressant - Both Stimulant and depressant action on spinal cord

neuroendocrine function

For analgesic

Dogs @ 0.01 -0.04 mg/kg IM, SC, IV repeated in 4-8 hrs interval

Cats@ 0.005 -0.01 mg/Kg IM, SC, IV  repeated 4-8 hrs intervals

0.01-0.02 mg/kg PO Transmucosal (buccal and sublingual) 2-4 times daily

Horses @ 0.005 - 0.02 mg/Kg IM, SC,IV

Pigs @ 0.005 - 0.02mg/kg IM, SC, IV 2-4 times daily

Sheep & Goat - 0.005 -0.1 mg/kg IM 4-6 times daily

Primates 0.005 -0.01 mg/Kg IM, SC, IV repeated in 4-8hrs interval

For sedation

Dogs - 0.01mg/Kg IM may be repeated after 12 hours 

Cats @0.005-0.01mg/kg SC or IM

For Neurolept analgesia

Dogs & cats @ 0.01mg/kg IM in combination with acepromazine (0.03mg/kg)

Not used in impaired respiratory function

Additive effect

INJ BUPREVET

• 10 ml vial
• 0.3 mg/ml

INJ BUPRELIEVE

• 10 ml vial
• 0.3 mg/ml

Psychoactive

Anxiolytic

Serotonin 5HT1A  Partial agonist

Antianxiety

Marked sedation

Interference with psychogenic performance

For low grade anxieties & fear

Dogs

2.5 - 10 mg (Total dose) PO 2-3 times daily

Cats

0.5 - 1 mg /Kg  PO 2 to 3 times for 6 -8 weeks

For indoor urine spraying 

Cats - 8mg (Total dose)  PO 2 times daily

Renal or hepatic disease

Epilepsy, Aggression animals

Cats - Increased aggressiveness, mild sedation, increased affection, friendliness and attention seeking behaviour agitation

Oral - vomiting dizziness, drowsiness, miosis, gastric distension

TAB BUSPIN 10

Antidote for Arsenic , Mercury, gold poisoning

Bidentate chelator containing two sulphhydral or thiol (SH) groups

Antidote for Arsenic , Mercury, gold poisoning

Dogs and Cats

2.5-5mg/Kg IM repeated every 4 hours for first 1-2 days, every 6 hours for 3rd day and 2 times for next 4 - 10 days until recovery

Large animals

3mg/Kg  IM repeated every 4 hours for first 2 days, every 6 hours for 3rd day and 2 times for next  10 days until recovery

Seizures in higher doses

Rise in BP, Tachycardia, Burning sensation, Inflammation of mucus membrane, sweating, cramps and headache

Hepatic insufficiency patients

Iron, Selenium and Cadmium poisoning

Poisoning form ASH3 (Arsine gas)

Impaired renal function

B.A.L., Dierlnic 100, R- Caprol, Liv Caprol

Non steroidal anti inflammatory drug

cox 2 inhibitor

Osteoarthritis, postoperative pain- associate with soft tissue and orthopedic surgery in dogs

Dog - 0.5 mg/kg

Tablet firotail 227mg

Tablet previcox 227mg

Neuroleptics analgesia

Fentomyl- act on u-opioid receptor

Droperidol- ontasonist of dopamine in CNS

Minor surgery, restraining agent in aggressive dogs

Dog- 0.1-0.15 mg/kg I/M

0.04-0.08 mg/ky I/V

Cat - 0.1 mg/kgI/C

Not used in food animals

Steroid hormone

Steroid hormone produced by Adernal cortex and used medicinally to treat inflammation resulting from eczema 

Works by calming down body's immune response to reduce pain, itching and swelling

Inflammation

Acute and chronic insufficiency

1 to 2.5 mg/pound for anti-inflammatory effects

Diabetic patients

Fungal infection

No adverse systemic effects

Ointment:hydrocortisone 1%w/w

Spray Cortavance - 76ml

Infusion

Used to treat or prevent hypovolemia (decrease blood plasma volume also called "shock")that may occur as a result of serious injury,surgery,severe blood loss,burns or other trauma

Congestive heart failure

Oliguric/Anuric renal failure

10-15ml/kg:dogs

5-10ml/kg:cats

Severe hypernatremia

Severe hyperchloremia

Intracranial bleeding

NA

Hydroxyethyl starch- 500ml

Injection HETSTAR-450 ml

Inj Hespan 500ml

Anticonvulsant

Inhibition of voltage gated N - type calcium channels in the CNS

Anticonvulsant, Analgesic, Chronic seizures, Chronic pain syndrome

Fir epileptic seizures ( as anticonvulsant) 

Dogs and cats- 2.5-10mg/kg -2-3 times daily

For neuropathic pain (as analgesic) 

Dogs and cats -2-5 10 mg/ kg  for 2-3 times ,daily limited dose gradually increase upto 10-15 mg / kg for 2-3 times daily over 4 weeks

Sedation, ataxia, fatigue, diarrhoea

TAB VETINA GABAPENTIN 100 mg

Expectorant, Skeletal muscle relaxant

Increasing the volume and decreasing the viscosity of secretions in bronchi and trachea 

Centrally acting muscle relaxant, expectorant, anticonvulsant. 

Cattle, Sheep, Goat- 66-140mg/kg IV SD

Horse-140mg/kg IN SD

Diabetes, glaucoma, Hypertension, Constipation, seizures

Mild Hypotension, Tachycardia, Hemolysis

Broxovil, Pedicoril, Mucinex, Bidex 400,Organidin NR

Antisecretory, Antispasmodic, Pre-anaesthetic 

Antimuscarinic

Adjuvent to general anaesthesia to decrease salivary and tracheobronchial secretions and to treat sinus bradycardia Or Incomplete AV block, Decrease acid secretion in stomach, stomach ulcers

Dog and cats- 5mg/lb adjuvant to anaesthesia 15 min. 's before anesthesia, 0.018-0.024 mg/ kg I/m

Mainly adverse effects are concerned 

Dry mouth, constipation, Decrease in urination, increased sensitivity to light, blurred vision, drowsiness

Inj Pyrolate

• 1 ml ampoule
• (0.2mg/ml)

Solution Cuvposa

• 473 ml bottle
• 0.2mg/ml

Glycolate-2 (2 mg tab)

Inj Licolate

• 1 ml ampoule
• 0.2 mg/ml