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Diuretic

Carbonic anhydrase inhibitor

• Glaucoma
• Raise the seizure threshold to convulsions in CNS

Dog @ 
5-10 mg/kg PO q8hr (Glaucoma)
4-8 mg/kg PO q8hr (other diuretic uses)

Cat @ 
50 mg (Total dose) IV Once
7 mg/kg PO q8hr 

Cattle, Sheep and Goat @ 
6-8mg/kg IV IM SC

• Hepatic disease
• Renal insufficiency
• Fluid electrolyte imbalance
• Hyperchloremic acidosis

• Hypokaelemia
• Hyponatremia
• Hyperuricosaemia
• Metabolic acidosis
• Renal calcus
• Skin toxicity
• Allergic reaction
• Bone marrow depression

Tab. Diamox

150 mg
250mg

Tab. Act-One-250

250mg

• NSAIDs
• Potent Analgesic 
• Potent Antipyretics

• Acetaminophen - COX inhibitor
• Codeine - act on μ-receptor in CNS

• Severe pain

Dog @ 1-4mg/kg PO 3-4 times daily

• Asthama 
• Diminished respiratory reserve patient

• GI ulceration
• CNS and respiratory depressant on high dose

Oxymark-CD

Synthetic hormones

Short acting oestrogen

Management of urethral sphincter mechanisms incompetence (develops in spayed bitches)

Dog - (PO q24hr)

Initial dose - 1mg/dog

If treatment is successful- dose reduce to 0.5mg/kg

If treatment is not successful- dose increase to 2mg/kg

Intact bitches

Intact bitches

Hormonal therapy

Increase the estrogen secretion endogenously 

To induce estrus (heat) or estrus behavior and for long term treatment of urinary in continence in horses

• also used in dogs and cats as mismate treatment to avoid pregnancy

• anovulatory mare:- 2.5 mg of estradiol followed by 1500 mg of progesterone

• For mismating dogs:- 0.02-0.04 mg/kg I'M in dogs within 40 hours of mating 

• cats :- 0.125-0.25 mg/kg I/M

Should use with caution in

• Intact female dogs

• Pregnant or Lactating dogs

• Male dogs and dogs of less then one year of age 

Endometrial hyperplasia 

• pyometra 

• leukopenia 

• thrombocytopenia 

0.5mg, 1mg, 1.5mg or 2mg tablets

• estradiol cypionate 

• ECP pharmica (on cattle) 

Inj. Pregheat 2ml vial (1mg/ml)

Antibiotic 

4th generation cephalosporin 

Mostly against gram negative

Inhibit synthesis of bacterial cell wall

Mastitis (E. coli)

Respiratory infection 

Cattle @ 1mg/kg IM OD for 2 days in Mastitis and 2.5 mg/kg IM q48 hr in respiratory disease 

cat and dog @ 2mg/kg IV IM SC q12hr

horse @ 1mg/kg IV IN q24 hr for 5-10 days in respiratory infection 

Hypersensitive animals

In hypersensitive animals

Cobactan - Syrup 50ml(25mg/ml)

Antibiotics

3rd generation cephalosporin 

bactricidal

broadspectrum

Inhibit bacteria cell wall synthesis 

Skin infection 

GI tract, urinary tract, lower and upper respiratory tract infection 

Cat @ 5 mg/kg PO BID or 10mg/kg PO OD

dog @ 5-10mg/kg PO OD 5-7days for skin infection and 5-10mg/kg BID for staphylococcal kin infection 

Renal impaired patients 

hypersensitive patients

Vomiting

diarrhoea

Cefpet - Tab 100mg, 200mg and Syrup 30ml (100mg/5ml)

Cef Dp - Tab 100mg, 200mg

Microcef - Tab 50mg, 100mg

Kefodoxime Vet Dt - Tab 100mg, 200mg and suspension 30ml (50mg/5ml and 100mg /5ml)

Third generation cephalosporin.

Interfere with bacterial wall synthesis by inactivating transpeptidase enzyme

Bactricidal

Intra abdominal infections

Respiratory tract infections

Localized infection

Urinary tract infection

Cat & dog @ 10mg/kg BID

Penicillin hypersensitive animals

Be cautious in penicillin hypersensitive animals 

Cefix

Tab 100mg and 200 mg

Cefspan 

Suspension 30ml (100mg/5ml)

Ceftas

Tab 100, 200, 400mg

Selective prolactin inhibitors

Dopamine receptor agonist

Ergot derivative 

Reduce the amount of prolactin from pituitary gland

Induction oestrus

pseudopregnancy in bitches

induce abortion in queens and bitches

pituitary adenoma in rats

For pseudopregnancy@ 5mcg/kg PO for 5-10 days

For pregnancy termination @ 5mcg/kg PO for 5 days (at 30 days in cats and after 40 days in dog)

for oestrus detection @ 5mcg/kg PO OD induces fertile pro oestrus in 4-25 days and administer until onset of oestrus.

Cause abortion 

dopamine antagonist will counteract effect

anti hypertensive drugs will cause hypotension 

Cabgolin - Tab 0.25mg, 0.5mg

Colette - Tab 0.5mg

Expectorant

Mucolytic action by distrupting the structure of acid mucopolysaccharide fibres in mucoid sputum and produces viscous mucus

Promotes secretion of sputum liquifying mucus

Done by breaking acid polysaccharide fibrous structure present in sputum

Respiratory distress, Cough due to pneumonia and bronchitis

Cattle, Sheep and Goat

0.2 to 0.5 mg /Kg BW, OD, PO or IM

Dogs

1.6 to 2.4 mg /Kg BID PO

3-15 mg/ dog IM PO BID

Cats

1mg /Kg BW OD PO

3mg/ Cat IM OD

Horse

0.1 to 0.25 mg /Kg OD, IM, PO

Birds

1.5mg/Kg  BID IM, PO, OD

Hypersenstivity or idiosyncratic reaction to bromhexine

Rhinorrhoea 

Lacrimation

Bromhexime Tab 5mg

Syrup 3mg/5ml