Categories: Uncategorized

Hydroxy progesterone / Progesyn / P Depot / duraprogen / gestabliss

HYDROXY PROGESTERONE

Category

Progesterone preparation

Action
  • Maintains the endometrium and is important for the continuity of pregnancy
  • Promotes mucus formation in vagina, participates in development of alveolar system in mammary gland
  • At low dose, cause ovulation
Indication
  • Habitual / threatened abortions due to inadequate progesterone level
  • Uterine prolapse
  • Repeat breeding due to failure of embryo implantation as a result of luteal insufficiency
Dose

Route - IM

Habitual abortion indications in Early pregnancy - 3ml IM after 45 days of pregnancy and to be repeated 4-5 times at every 10 days interval

Habitual / threatened abortions ( mid / late pregnancy ) - 3ml IM for 3 days and followed by weekly injection for next 3 weeks

Uterine prolapse (due to pronounced heat) - 3 ml IM to be repeated on 3rd day, if required

Post partum uterine prolapse - 3 ml IM at every alternate day, followed by weekly injection for 3 weeks

Anti partum uterine prolapse - 3 ml IM at 2 days interval for 3 times

Repeat breeeders (with luteal insufficiency) - 2-3 ml IM at 5th, 12th and 19th days post Al .

Contraindications
  • Prolonged exogenous administration - Uterine glandular hyperplasia, uterine fluid accumulation, endometritis
  • Pregnant animal
Adverse Effects
  • Pain at site of administration
  • Allergic skin rashes
  • Urticaria may be encountered
Availability

Inj. PROGESYN (INTAS)

  • 3 ml ampoule
  • Each ml contains

Hydroxyprogesterone caproate IP........0.25g
Benzyl alcohol IP........0.02ml (as preservative)

Inj. P Depot (ZYDUS)

  • 2ml, 3ml ampoules
  • 250mg/ml

inj duraprogen (VETCARE)

  • 2ml ampoules
  • 0.25gm/ml

inj gestabliss (VET MANKIND)

  • 0.25gm /ml
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