Inhalant anaesthesia

• Uncertain
• Interferes with functioning  of nerve cells in brain produce generalized, reversible depression of CNS

Induction and maintenance of anaesthesia

Small animals

• Induction:5%
• Maintenance:1.5-2.5%

• Patients with predilection towards malignant hypertension
• Use caution in patients with high CSF, head surgery, myasthenia gravis
• Irritant to respiratory system

• Hypotension
• Dose dependent respiratory depression
• Cardiodepression
• GI disturbance