Acetaminophen / Capol / Poenophen / Rapidmol ACETAMINOPHEN CategoryNSAIDsPara-aminophenol derivative having analgesic and antipyretic properties ActionInhibition of Cyclo oxygenase (COX) enzyme More selectively for COX-2 than COX-1Anti-pyretic and analgesic effectIndicationOral analgesic in dogRelieve painFever reducerDoseDog @ 15 mg/kg POCalves @ 50 mg/kg PO followed by 30 mg/kg PO q6h ContraindicationsFatal for CAT (lack of Glucuronyl transferase enzyme that is responsible for metabolism of drug)In dog if renal or hepatic diseaseAdverse EffectsCan cause hepatic and renal toxicity Hb → methHb → SulfHb HaemolysisJaundiceAvailabilitySusp. Poenophen - 50 mg/ml (60 ml Bottle) - (MVDEX)Infusion Rapidmol - 1%w/v (100ml Sachet) IVSusp Calpol - 60mlTab Calpol - 500mg DOSE CALCULATOR
Acepromazine / VetAce ACEPROMAZINE CategoryTranquilizer Sedative ( Phenothiazine derivative)ActionDepressant effect on CNS Depressant effect on various central neuro-transmitter receptorsIndicationImmobilize large animalsSkin irritationPre-anaestheticSedativeIn Small animal- Anti-emetic to control vomiting associated with motion sicknessDoseDog @0.1-o.25 mg/kg IM0.025-0.2 mg/kg IV (slow)0.25-3 mg/kg POCat @o.o5-o.1 mg/kg IM/IVo.25-3 mg/kg POCattle, Sheep & Goat @0.03-0.1 mg/kg IM, IV, SCHorse @0.04-0.1 mg/kg IM, IV, SC ContraindicationsNot safe in pregnancyStallion with penile prolapseLactating mareHorse dewormed with piperazineSighthound & Boxer breed are sensitive (cause first degree heart block)Pets that have been exposed to organophosphates, strychnine, or procaineTraumaShockAdverse EffectsCause low blood pressureIn cats, decrease tear productionIt can cause cardiovascular collapseAvailabilityTab. VETACE - 25mgInj. Acepromazine (VET ONE) - 10mg/ml (50ml vial) DOSE CALCULATOR
