Anti fungal

It cause pore formation in fungal cell wall that leads to leakage of K+, Na+, H+ and Cl- and cause fungal death 

Systemic fungal infection

leshmaniasis

Cats @ 0.1-0.25 mg/kg IV every 48 hours

dogs @ 0.2605-1mg/kg IV every 48 hours

Horses @ 0.3-0.6mg/kg IV  slow dilute 24-48 hours

Severe lever dysfunction

Nephrotoxicity

Amphocil

Ambisome

Fungizone 

Abelcet