Antiprotozoal (carbanilide diamidines) 

• Not clear
• Combining with protozoal DNA causing DNA to unwind and denature & interferes with DNA synthesis

• Antiprotozoal spectrum: babesia, cytauxzoon, hepatozoon, anaplasma, Ehrlichia.       Babesia (canis, gibsoni, caballi) 
• Intracellular tick borne pathogens
• Babesiosis, anaplasmosis, Ehrlichiosis, cytauxzoon folis infection

In cats not used

Horse @ 2.4 mg/kg IM

Cattle & Buffalo @ 3-4mg/kg IM

Dog @ 6.6mg/kg IM SC Once (Repeat in 2-3weeks)

• Low therapeutic index
• Mild cholinergic signs
• Anaphylaxis
• Pain at injection site
• Hepatic and renal impairment

Inj. Imizet (INTAS)

• 5 ml and 10ml vials
• 120mg/ml