Hormone

Direct luteolytic action

• Terminate pregnancy
• Estrous synchronisation
• Induction of parturition 
• Pyometra

Cattle:

•     Abortion= 25mg total dose once I/M
•     Synchronisation= 25mg I/M for 10-20 days
•     Pyometra = 25mg

Dog:

• Abortion= 0.025-0.05 mg/kg q 12hrs I/M
• Pyometra= 0.1-0.2 mg/kg S/C

Hepatic, renal, systemic disease in pregnancy except MTP

• Decrease appetite
• Cramping
• Sweating

• Injection Lutalyse 5ml,10ml (5mg/ml)
• Injection Pro Dino 5mg/ml

Prostaglandin F2α preparation

• Potent luteolytic agent
• It cause functional and morphological regression of the Corpus Luteum

• Drug of choice for endometritis in Cattle
• Anoestrus due to ovarian luteal cyst
• Silent / sub oestrus
• Termination of abnormal pregnancy (mummified foetus)
• Treatment of unwanted pregnancy
• Hydrops of foetal membranes
• Chronic endometritis / pyometra
• Induction of parturition
• Herd management
• Termination of pseudopregnancy
• Barren and maiden mares
• Synchronisation of oestrus

Cattle and Buffalo @

2ml (500mcg) - IM

Horses @

• Single IM Inj.  of 0.5-1 ml (mare have upto 400kg b.wt)
• 1-2 ml IM Inj (mare have more than 400kg b.wt)

Sheep and Goat @

0.5 ml (125 mcg) IM

Cat @

5 mcg/kg SC once daily for 3 days

Dog @

1-1.25 mcg/kg OD SC for 4-5 days 

• Pregnant animal (cause threatened abortion)
• Mare suffering from acute or subacute GI disorders and respiratory disease
• IV route is contraindicated

(Skin absorption is there, so take care during handling)

• Increased cardiac and respiratory rates
• Abdominal discomfort
• Watery diarrhoea
• Depression
• Vomiting and Nausea

(These signs are transient and last for 15-20 minutes)

Inj. PRAGMA (INTAS)

• 2 ml, 10 ml vials
• Each ml contain 250mcg

Inj. PREGOVA (VIRBAC)

• 2 ml vials
• Each ml contain 263 mcg 

inj pg estro (HESTER)

• 2ml vials
• 250mcg/ml

Inj. ESTRUMATE

• 20 ml vials
• Each ml contain 250mcg

Inj. CLOSTENOL

• 2 ml vials
• Each ml contain 250mcg

Inj. ALPHA TWO

• 2 ml vials
• Each ml contain 250mcg

Calcium supplement 

Hypocalcemia

Slow IV 

Cattle and buffalo - 250-300 ml/day Single dose (but can be repeated in severe cases)

Sheep and goat - 25-50ml

Rapid IV is contraindicated 

Raid IV is contraindicated 

Inj Calborol - 450ml bottle

Inj calcium borogluconate (VETOQUINOL) - 450 ml bottle 

Inj Mefix - (Calcium + Magnesium + Phosphorus) - 450 ml bottle

Local anesthetic, eye curer

Local anesthetic with reversible blockage of sodium channel, preventing the propagation of action potential

Application on eye, external ear and nares

Dog- 1-2 drops /eye or 5-10 drops / ear or nose

Cat- 1-2 drops / eye

N/A

Blurred vision, sensitivity to light

Eye drop propacaine (0.5%) 5ml