Ovulation inducer

Inhibit negative feedback mechanism of oestrogen on GnRH, enabling the release of GnRH from hypothalamus , inducing ovulation

Anovulatory oestrogen, repeat breeding, delayed puberty, oestrogen induced tumors

Horse, cattle, sheep , goat @ 1-1.5 mg/Kg for 5 days

dog @ 25mg/kg

In anoestrus and repeat breeding cattle @ 300mg for 3-5 days

Precaution- administer 1% copper sulphate solution before clomiphene to induce closure of rumens reticular groove.

In pregnant animals 

Clomifert 

Tab 300mg

Fertivet 

Tab 300mg

Fertotab

Tab 300 mg

Fertyl

Tab 50mg

Omicite

Tab 50mg

Siphene

Tab 50 and 100 mg

Hormone (OG)

Mimics the effect of pituitary LH carving ovulation, promote formation and maintenance of CL

In females induces follicular maturation, ovulation and development of CL. 

In males stimulate testosterone secretion

To induce lactation post partum

In bitches who hold to mating 

Dog - delayed ovulation - 22 IU/kg

Anestnu - 500IU/dog

Postpartum- lactation failure 100-150IU with systemic oxytocin

Deficient male libido/Cryptorchidium 100-1500 IU/dog

Cat - not used 

Cattle- Repeat breeding 1500-3000 IU (I/M) 

Cystic ovaries: 1500-3000 IU as I/M repeat on 8th day if CL in poorly developed 

Fatal resorption - 1500-3000 IU for 4 weeks as I/M

No info available

Stomach pain, stomach bloating and weight gain

Injection chorulon 1500 IU vial

Laxative, purgative

• Surfactant stool softener
• Increase cAMP concentration turn 
• Increase fluid permeability and ion secretion from colon mucosal cells

Painful defecation

Dog:

• Docusate sodium= 20-50mg PO once/twice
• Docusate calcium= 50 mg capsules q 12-24hrs PO

Cattle = 20g total dose

Not used with pre existing electrolyte/water balance

• Allergic reaction
• Breathing problem
• Muscle weakness

• CoLACE 60 capsule
• DULCoLAX 100 Capsule
• Docusate Sodium bloat preparation - 240mg/1fl.
• Docusate sodium enema - 5%
• Docusate sodium enema - 250mg in 12ml
• Docusate sodium oral liquid 5% in gallons

Laxative and purgatives

It is a disaccharide

It to reach the colon and metabolised by the resident bacteria, resulting in formation of lactic formic acetic and CO2.

it increase the osmotic pressure that is drawn the water into Bowel causing a laxative effect and also as acidify colonic contents

Laxative in a small animals

Reduce ammonia blood levels in the prevention and treatment of hepatic encephalopathy

In cats

for constipation - 1ML per 4.5 KG of body weight and dose can be adjusted as needed.

For Hepatic encephalopathy - 0.25 - 1ml PO 

In dog

For constipation - 1ML per 4.5 KG or bodyweight and dose can be adjusted.

For Hepatic encephalopathy - 15 to 30 ML PO four times a day and dose can be adjusted

In diabetic patient

Syrup contains some free, lactose and Galactose that may alter the insulin requirements

Lactulose solution - 10gm per 15ml, 30ml, 240ml, 473ml, 480, 960, 1893ml

Lactulose crystals 10gm, 20gm

Broad spectrum antibiotic 

Inhibition of protein synthesis 

Mastitis

matritis

bacterial enteritis

pneumonia

urinary tract infection

foot rot

Meningitis

hepatitis

otitis

ocular infection

rickettsial disease

Bovine @ 2-4mg / kgbBID IV and 20-30mg/kg IM

Sheep and goat @ 10mg/kg BID IV and 30-40mg/kg IM

dog @ 25-50mg/kg IV

Pups

Toxicosis in cats - CNS depression, vomiting, weight loss, dehydration and inappetance

aplastic anemia

reversible bone marrow suppression 

Chloramphenicol sodium succinate - Inj 1gm

Chloraxin - Inj 3gm

Chlorcetin vet - Inj 3g

Chlorophen - Inj 150mg/ml (30 ml)

Chlorovet - Inj 100mg/ml (30ml )

Lykacetin - Inj 1gm, 2gm, 3gm

Antibiotic

• Bovine mastitis 
• causative organism is not known
• penicillin resistant bacteria are known 

Intra mammary only

Tilox ( VETOQUINOL)

• 6 * 5 single dose
• Each 5gm contains 75mg ampicillin + 200mg Cloxacillin)

Third generation cephalosporin 

Binds to penicillin binding proteins which inhibit final transpeptidation and cause lysis of bacteria cell wall

Haemorrhagic septicemia, animal black quarters, cystitis, nephritis, meningitis, metritis, mastitis, pyometra, preoperative prophylaxis, post operative care

5-10 mg/kg IV IM SC

Penicillin hypersensitive animals

Cause cross resistance in penicillin hypersensitive animals

Mammicef (INTAS) - 10 ml pre-filled syringe (250mg cefoperazone)

Mammitas (INTAS) - 3.5 gm pre-filled syringe (3.5 gm  Cefuroxime) - one syringe per quarter every 12 hours for 3-4 times but in chronic cases, 8 times can be infused

Mastiwok ( VETOQUINOL) - 10 ml pre-filled syringe (250 mg)

Mamiprotec (VIRBAC) - pre-filled 10 ml syringe (250 mg cefoperazone)

Cefomycin

Inj 1gm

Magnamycin

250mg, 1g, 2g

Inodilator

A calcium sensitive and a selective inhibitor of phosphodiesterase |||(PDE |||) and having positive ionotropic and vasodilator effect. It increases cardiac muscle contractility

Valvular insufficiency, increases the rate of survival chances in dogs

Dogs- 0.5 mg/ Kg daily dose PO ( can divide the daily dose into two portions and can be given 2 hrs apart) 

Cats - 0.1-0.3 mg/ kg q 12 h PO

Hypersensitive patients, pregnancy safety, resorption may occur at high dose rate

Diarrhoea, vomition, low appetite

Safe heart tab. 1.25mg, 5 mg, 10 mg, Petmedin tab 2.5 mg, 5 mg, 10 mg

Immunosuppressants

T lymphocytes inhibition 

Atopic dermatitis 

Perinial fistula

subaceous adenitis

immune mediated kerato conjunctivitis sicca

Cat @ 7mg/kg/day for atopic dermatitis 

dog @ 5mg/kg PO 24hr for perineal fistula, sebaceous adenitis, immuno mediated disease

Progressive malignant disorders 

Not used in progressive malignant disease 

Imusporin - Capsule 25mg, 50mg, 100mg

Ichmune C - Tab 25mg, 50mg and 100mg

Visocare eye ointment - 3.5gm

Optho eye care - Drops 5ml

Atropica - Suspension 5ml(100mg/ml) for cats

Hematinic

Iron is necessary for myoglobin and haemoglobin in the transport and utilization of oxygen

• Treatment and prophylaxis of Fe deficiency
• Anaemia

• Ruminants: 10-30 mg/kg, 24 hrs,  PO
• Horse: 10-20 mg/kg, 24 hrs,  PO
• Dog: 100-300 mg/dog, 24 hrs,  PO
• Cat: 50-100mg/cat 24hrs,   PO

• Anaemia other than iron deficiency
• Acute renal infections
• Conjunction with oral iron supplements

• Prostration
• Muscle weakness
• Anaphylacoid reaction

Inj. Imferon 2ml (50mg/ml)