Gen. Anesthetic

2,6 diisopropylphenol, mechanism not fully known, evidence suggests that it acts through potentiation of GABA receptor activity, thereby Cl channel closing time slow down

Induction or maintenance of anasthesia using continuous or intermediate rate infusion

Without premedication

Dog/cat- 6mg/kg

Small animal- 4 mg/kg 

Pig- 2. 5 mg/kg

With premedication

Dog and cat- 2.5-5mg/kg IV

Maintenance

Dog/cat- 2.5-5 mg/kg IV

For sedation/ seizure-

Dog/cat- 0.1-0.2mg/kg Iv

Hypersensitivity, hepatic and renal diseases, hypervolumic patients, impaired left ventricular atrium 

Dizziness, blurred vission

Propovon

• 1o ml, 20ml vial
• Each ml contains 10 mg

Troypofol

• 20 ml vial (1% w/v)

General anaesthetic and sedative. 

• Dissociation agent- causes profound analgesia, immobility, amnesia.
• Primarily act on the cortex.
• Inhibit glutamate receptor and NMDA receptors. 

• Visceral and somatic analgesia
• Increased muscle tone
• Chemical restraint

Without premedication

Cat @ 11-33 mg/kg IV / SC / IM

With premedication

• Cat @ 22mg/kg IM
• Dog @ 5-10mg/kg IM
• Cattle/horse/sheep/swine/goat @ 2mg/kg IV and 10mg/kg IM 
• Primates @ 2-4 mg/kg IV and 10-15 mg/kg IM

For restraint

• Cat @ 11mg/kg IM

• Epilepsy, renal and hepatic injury, hypertension, unstable angina, increased intracranial Or intraocular pressure, heart failure. 
• Corneal drying due to open eyes - bland ophthalmic ointment in eyes. 
• Combination with alpha-2 against  - may lead to vomition in some cases. 

• Ketamine should not be used in animals with hypertension, heart disease, liver disease, kidney disease, seizures  and hypersensitivity to drugs. 
• Ketamine doesn't relax the muscles at the back of the throat, so it should be avoid in procedure involving the pharynx, larynx and trachea. 

inj ketamin (THEMIS MEDICALS)

• 5 ml vials
• 50 mg/ml

Inj. Aneket

• 10ml vial
• (500mg/10ml) 

Inj. Zokent-2

• 2ml Amp
• (100mg/2ml) 

Inj. Zokent-10

• 10ml Amp
• (500mg/10ml) 

Inj. Ketaset

• 10ml vial
• (1000mg/10ml) 

Inj. Vetaket

• 10ml vial
• (1000mg/10ml) 

General anaesthesia,  Pre anaesthetic (Benzodiazepine), Tranquilizers,sedative.

Increasing the effect of GABA on its receptor.

Sedation, Amnesia, seizure, pre anaesthetic induction. 

Dog

Seizure - 0.2 to 0.3 mg / kg (IV)

Pre anaesthetic- 0.2 to 0.4 mg / kg (IV).

Induction- 0.1 to 0.2 mg /kg (IV).

Sedation- 0.1 to 0.4mg /kg (IV, IM, SC)

0.2 to 1 mg/kg( Intra nasal).

Cat

Induction- 0.3 to 0.6 mg/kg (IV with ketamine)

Sedation - O.1 to 0.4 mg /kg ( IV,IM,SC)

Horse 

Pre anaesthetic- 11 to 44 mcg per kg IV

Induction-0.1 mg/kg IV

Sedation- 0.5 -0.2 mg / kg IV

Birds

Pre anaesthetic- 0.1 to 0.5 mg /kg (IM)

Pig

Induction-0.5 mg per kg with ketamine  IV.

Cattle 

Induction-0.1 mg/kg IV

Sedation-0.1 to 1 mg per kg IV.

Myasthenia Gravis in neonates.

Avoid in myasthenia gravis

Inj:

Benzosed 5ml,10ml(1mg/ml).

Midez-5ml ,10ml(1mg/ml,5mg/ml).

General anesthesia, Sedative

Short acting barbiturate acts by potentiating GAB and inhibits chloride channel opening 

Anesthetic, emergency control of seizure, euthanasia

General Anaesthesia

Dog and cats -25 -30 mg /kg I/v

Swine and calves-  15-30 mg /kg I/v

Sheep and goat -20-30mg/kg I/v

For stature epileptices

Dog and cat 5-15 mg/kg body

Hypnotic and anxiolytic- 2-20 mg /kg I/v

Euthanasia - 120-200 mg/kg I/v

Hypovolumia, anemic, cardiac and respiratory disease, not recommended for caesarian section

Bradycardia, confusion, dizziness, low blood pressure

Injection- Euthasol-100 ml (Euthanesia) 

General anaesthesia

Suppression of reticular activation in system of brain stem

Induction of anaesthesia piror to inhalation maintenance

Without premedication        cat & Dog - 20 to 30 mg /kg IV ,  Cattle & Horse - 8-15 mg/Kg, pig - 10 to 20 mg/kg, sheep & Goat -20 to 25 mg /kg  IV

With premedication                Dog & cat - 8 to 12 mg/kg IV, Cattle & Horse - 5.5 mg/Kg IV

Hypersensitivity, Ischemic necrosis, arteriospasm, Shock

Coughing, Sneezing, Slow breathing, cardiac arrthymia, Shivering

THIOSOL 500 mg, 1g            THIOPEN 500 mg, 1g            THIOTONE 500 mg, 1g

Hormones

Secreted from the endometrial cups of pregnant mare in early pregnancy by developing and ovulating follicles to maintain primary corpus luteum

Stimulate ovarian follicle growth in anoestrous sheep, goat and cattle, to induce superovulation of downer cow in embryo transfer, mating synchronization

Cattle-1500-3000 IU , result in 3-5 days if needed repeat after 16-14 days

N/A

Ovarian hyper stimulation syndrome

Folligon PMSG

• One box contains 5 vials (1000 IU each) with 5 vials of solvent for reconstitution
• Each vial contains Pregnant Mare Serum Gonadotrophin (PMSG) as a white freeze dried crystalline powder (1000 I.U.)

• Hormone
• Oestradiol analogue

In combination with progestin to induce oestrus

Reproductive disorders like anoestrus and sub-oestrus

2 mg per animal IM

NA

NA

Inj Pregheat (VIRBAC)

• 2 ml vial
• Each ml contains 1 mg Oestradiol benzoate and o.1 ml benzyl alcohol

• Erythropoiesis stimulating agent

• Erythropoietin
• RBC Production increases

Chronic anaemia with cKD

• Dog-1mcg/kg once per week
• Cat-1mcg/kg once per week

Pregnancy safe

• Breathing problems
• Decrease amount of urine
• Chest pain

• Cresp s/c only- 40mcg/0.4ml
• Dargen 25-25mcg/0.4ml

Ectoparasiticides

Juvenile hormone analogue,

Inhibits larval development 

Ectoparasitic infestation. 

NA

Rabbits ,birds.

NA

Spray

Fixotic Advance spray - 100ml.

Spot on

Fixotic advance - 0.67ml,1.34ml,2.68ml,4.02 ml.

Fibrous plus 

Quickie plus,

Nayflec plus 0.5ml,

Tick fee -0.67ml

Ectoparasiticides

GABA gated chloride channel blocker 

Flea and ticks control

0.25% w/v

Human carcinogen, toxic to nervous system

Toxic to nervous system if ingested 

Fixotic advance spray (VETOQUINOL) - 100 ml ( 0.25% fipronil + 0.22% S-methoprene w/v)

Fixotic advance spot on (VETOQUINOL) - 0.67ml, 1.34ml, 2.68ml and 4.02ml ( 9.8% fipronil + 8.8% S-methoprene w/v)

Spray effipro (VIRBAC) - 80ml

spot-on effipro (VIRBAC) - 2 pipettes pack of 3 sizes small(4-10kg), medium (10-20kg), large(20-40kg)

Spray ticks free 100ml

Spray nay flee plus 100 ml

Spray quicfip 100ml and 200ml

Spray medipet 100ml