Propionic acid derivatives (NSAIDs)

Inhibition of cyclo oxygenase, phospho lipase a2 , and prostaglandin synthesis.

Chronic inflammation 

pyrexia

pain

Dog @ 2-4mg/kg

Animal with bleeding disorders

Should be cautious in renal and hepatic insufficiency.

Care O pet 

Tab 50mg

NSAID

Block cox enzymes and inhibit prostaglandins synthesis

Cataract surgery for occular inflammation and Pain

Dogs and cats

1 drop/ eye for 6-12 hrs interval

Epithelial Keratopathy

Red eyes

Rheumatoid arthritis

Megabrom eyedrops

Eynac

Nunac

Napimox

broday

Prolensa

Cromtie

Bbrom

• Rumen acidifying agent
• Antiseptic
• Disinfectant

• Rumen acidifying agent - Decrease Rumen pH 
• Antiseptic - Destroy bacteria by liberation of H+ ions

• Ruminal stasis
• Urea toxicity
• 0.25% for urinary tract irrigation
• 1-3% for burn dressing
• Surgical dressing
• 5%  for bacteriocidal to treat Otitis externa
• 33% for ringworm lesion
• 99% (glacial acetic acid) for wart destruction

Cattle @

1000-2000mL PO

Sheep @

250-500mL PO

Horse @

250ml/450kg b.wt. PO (for enterolith prevention)

• Ruminal acidosis

• Metabolic acidosis
• Corrosive action on skin and mucous membrane

NA

• NSAIDs
• Para-aminophenol derivative having analgesic and antipyretic properties 

• Inhibition of Cyclo oxygenase (COX) enzyme 
• More selectively for COX-2 than COX-1
• Anti-pyretic and analgesic effect

• Oral analgesic in dog
• Relieve pain
• Fever reducer

Dog @ 15 mg/kg PO

Calves @ 50 mg/kg PO followed by 30 mg/kg PO q6h

• Fatal for CAT (lack of Glucuronyl transferase enzyme that is responsible for metabolism of drug)
• In dog if renal or hepatic disease

• • • Can cause hepatic and renal toxicity
    •  Hb → methHb → SulfHb 
    • Haemolysis
    • Jaundice

Susp. Poenophen - 50 mg/ml (60 ml Bottle) - (MVDEX)

Infusion Rapidmol - 1%w/v (100ml Sachet) IV

Susp Calpol - 60ml

Tab Calpol - 500mg

Tranquilizer Sedative ( Phenothiazine derivative)

• Depressant effect on  CNS  
• Depressant effect on  various central neuro-transmitter receptors

• Immobilize large animals
• Skin irritation
• Pre-anaesthetic
• Sedative
• In Small animal- Anti-emetic to control vomiting associated with motion sickness

Dog @

0.1-o.25 mg/kg IM
0.025-0.2 mg/kg IV (slow)
0.25-3 mg/kg PO

Cat @

o.o5-o.1 mg/kg IM/IV
o.25-3 mg/kg PO

Cattle, Sheep & Goat @

0.03-0.1 mg/kg IM, IV, SC

Horse @

0.04-0.1 mg/kg IM, IV, SC

• Not safe in pregnancy
• Stallion with penile prolapse
• Lactating mare
• Horse dewormed with piperazine
• Sighthound & Boxer breed are sensitive (cause first degree heart block)
• Pets that have been exposed to organophosphates, strychnine, or procaine
• Trauma
• Shock

• Cause low blood pressure
• In cats, decrease tear production
• It can cause cardiovascular collapse

Tab. VETACE - 25mg

Inj. Acepromazine (VET ONE) - 10mg/ml (50ml vial)