Antacids

Buffer mechanism of body

Severe metabolic acidosis

Cardiac arrest

Severe primary lactic acidosis

Severe diarrhoea

Alkalized urine

Adjuvant therapy for hypercalcemia/hyperkalemia induced crisis

Dog and Cat 

severe metabolic acidosis 8-12 mg/kg PO q 8hr

Goat and Cattle 

7.5% solution make it to 5% before IV

5% solution 5ml/kg

2/3rd 7.5% Sodium bicarbonate and 1/3rd NS

Hypocapnoeic patients 

Vomitting animals

Hypoventilating animals

Undesirable rise in plasma sodium concentration 

Hypernatremia

pH 7.4 injection 100ml 

Formulations 1.26%, 4.2%, 8.4%(pH 7.8) solution for slow IV

• Analgesics
• Antispasmodics

• Abdominal pain/colic
• Spasms of intestine

0.5-1mg/kg IV

• Headache
• Drowsiness
• Fatigue
• Vomiting
• Constipation
• Sweating
• Dryness in mouth
• Redness, pain, swelling at site of injection

Injection Fortwin

• 1ml ampoule
• Each ml contain 30 mg pentazocine

Antispasmodic 

Relieve smooth muscle spasm (Musculotropic)

• Visceral pain of GIT
• Prolapse of vagina,bladder,rectal
• Recto vaginal prolapse

• Ruminant= 0.5mg/kg  T. Dose-150mg
• Dogs= 5-10mg(total dose) PO

• Overactive thyroid gland
• Skeletal muscle disorder
• Myasthenia gravis

• Blurred eyes
• Dry eyes
• Dry mouth
• Constipation

• Dicyclo 20
• MEFTAL-SPAS
• Inj spasmovet (VETOQUINOL ) - 30ml vials (10mg/ml)
• Inj Ridalpin 30ml
• Tab cyclopam
• Inj cyclopam

• Analgesics
• Antispasmodics

Block the synthesis of prostaglandin in CNS

Release Beta-endorphin

•  Pain in colic and other spastic conditions of the abdominal organs
•  Acute and chronic arthritis
• Rheumatic conditions of muscles and joints
• Neuritis
• Neuralgia
• Obstruction of the oesophagus by foreign bodies-to relieve spam.
• In gastritis of small domestic animals to prevent vomiting.

ROUTE - IM (SC is contraindicated)

Cattle @  8 ml per 100 kg body weight 

Horses @ 20-60 ml 

Calves @ 5-15 ml

Sheep and Goats @ 2-8 ml 

Dogs @ 1-5 ml

• Do not use in cats.
• Do not use by subcutaneous route.
• Vetalgin should not be used in animals with disturbance of haemotopoietic system

• Long term use - Agranulocytosis
• Overdose - Convulsive seizure
• Neutropenia
• Analgin + Chlorpromazine - severe hypothermia

Injection Vetalgin® Vet

• 33m vial
• Each ml contains

Analgin I.P. ..... 0.5 gm and Chorobutol I.P. ......0.4 % w/v

• Analgesics-Antipyretics-Anti-inflammatory-Antispasmodics

NA

• Musculoskeletal Pain
• Lameness & Arthritis
• Post-Operative Pain
• Abdominal Pain 
• Fever

Large ruminants @ 4ml/100kg b.wt IM only

Small ruminants @ 1ml/100kg b.wt IM only

NA

NA

Injection Rumilide

• 30ml, 100ml vial

• Each ml contains NIMESULIDE 100 mg , PITOFENONE 2 mg, FENPIVERINIUM BROMIDE 0.02 mg

Analgesics
Antispasmodics

Block the synthesis of prostaglandin in CNS

Release Beta-endorphin

• Pain in colic and other spastic conditions of the abdominal organs
• Acute and chronic arthritis
• Rheumatic conditions of muscles and joints
• Neuritis
• Neuralgia
• Obstruction of the oesophagus by foreign bodies-to relieve spam.
• In gastritis of small domestic animals to prevent vomiting.

ROUTE - IM (SC is contraindicated)

Cattle @  8 ml per 100 kg body weight 

Horses @ 20-60 ml 

Calves @ 5-15 ml

Sheep and Goats @ 2-8 ml 

Dogs @ 1-5 ml

Do not use in cats.
Do not use by subcutaneous route.
Vetalgin should not be used in animals with disturbance of haemotopoietic system

Long term use - Agranulocytosis
Overdose - Convulsive seizure
Neutropenia
Analgin + Chlorpromazine - severe hypothermia

Injection Vetalgin® Vet

33m vial
Each ml contains

Analgin I.P. ..... 0.5 gm and Chorobutol I.P. ......0.4 % w/v

NSAID

Non selective cox inhibitor 

Used in pain and inflammation management in osteoarthritis condition

Dog- 15-22 mg/kg for 8-12 hr 

Cat - not used

Cattle-4-8mg/kg for 24 hr

Horse-4. 4-8.8mg/kg po 3-6mg /kg Iv

Elephant-3mg /kg po for 48 hrs or 2-4 mg/kg rectally

Cl in dehydrated, hypovolumic /hypersensitive patients, do not give to pregnant animals and aged animals

Diarrhoea, skin rashes

Injection- Artisone S 100 mL, Esgipyrin N 5 ml amp

Non steroidal Anti inflammatory drug

• Tolfenamic Acid has produced analgesic and anti-inflammatory effects by inhibiting the
  synthesis of prostaglandins.
• The enzyme inhibited by NSAIDs is the cyclooxygenase enzyme (COX).
• Tolfenamic Acid is a balanced COX-1/COX-2 inhibitor.

• All painful inflammatory conditions associated with Musculoskeletal Disorders, Respiratory Tract Infections, Mammary Gland Infections, Urogenital Tract Infections and Postoperative care
• Gel for Laminitis, Arthritis, Mastitis, Myositis, Bursitis, Sprains, Tenosynovitis/Tendinitis

Cattle and Buffalo: by IV/ IM Route: 4 mg/kg b.wt. as a single
dose or 2 mg/kg b.wt. to be repeated after 48 hrs.

Sheep and Goat: By IM or IV Route: 2mg/kg b.wt. as a single dose.

Pig: By /M Route: 2mg/kg
b.wt. as a single dose.

Horse: By IV Route: 2mg/kg b.wt as a single dose.

Dog- 4 mg/kg IM, SC repeated once after 24 hrs for 3 days                  

Cats -4 mg/kg SC repeated after 24 hrs PO for 3 days     cattle-2 mg/kg IM 48 hrs interval                               

• Animals prone to GI ulcers
• Do not administer with other ulcerogenic drugs such as corticosteroids.
• Not use in pregnancy

• Vomiting
• Diarrhoea

Bolus MAXXTOL - 500 (INTAS)

Inj. MAXXTOL - 30ml, 100ml  (40mg/ml) (INTAS)                       

Inj. MAXXTOL XP  - 20ml, 100ml   (80mg/ml)   (INTAS)

Gel - Maxxtol Top gel - 30 gm tube (INTAS)

Inj. Tolfine (VETOQUINOL)- Inj 30ml and 100 ml vials ( 4% and 8% available )

                       
Bolus. Tolfine (VETOQUINOL )- 500  mg

inj aletol (ALEMBIC) - 20ml vials (80mg/ml)

Top Gel Maxxtol - 30 gm tube 

• NSAIDs

• Pain
• Fever
• Pyrexia
• Musculoskeletal affections
• Lameness
• Postoperative therapy
• Uterine Prolapse
• Broncho-pneumonia
• Mastitis

Large animal @ 2 bolus BID

Small animal @ 1 bolus daily

Bolus pyridase

Each bolus contains

• Nimesulide B.P. 400mg
• Paracetamol I.P. 1500 mg
• Serratiopeptidase I.P. 75 mg

Bolus Bolin-NP (VETOQUINOL)

Each bolus contains

• Nimesulide B.P. 400mg
• Paracetamol I.P. 1500 mg

bolus serakind plus (VETMANKIND) - 60 mg serratiopeptidase

• NSAIDS

cyclooxygenase 2 inhibitor

• Osteoarthritis
• Myositis
• Bursitis
• Tenosynovitis
• Pyrexia
• Fever
• Inflammatory conditions
• Painful condition

Large animal @ 2-4 mg/kg b.wt

Small animal @ 0.5ml/ 10 kg b.wt

This drug must be used with caution in animals with liver and kidney dysfunction.

In addition, nimesulide has a range of other anti-inflammatory effects, including inhibition of the neutrophil oxidative response and inhibition of platelet activating factor

Oxalgin N P Injection

• 15ml, 30ml
• Each ml contains 100mg

Bol Bolin N P

• Management  of Pyrexia & Pain in cattle, buffaloes, sheep & goat. Supportive in Ephemeral fever.
• 2 boli twice daily