Antacids

Neutralize gastric HCl

Bind to phosphate in GI tract and making it unavailable for absorption 

Bind to pepsin and stimulate local PGE1 

Gastritis, gastric ulcers, hyperphosphatemia in cats and dogs

Cats and dogs @ 10-20mg/kg PO q6-8hr

0.5-1ml/kg PO q6-8hr after meal

prior administration of digoxin

Constipation 

Alucap, gelucil, acidex, mg salt (asilone, maolax, mucogel)

Cholagogues and cholerectic agent

It increases bile flow

Also decrease intestinal absorption of cholesterol

It reduces the hepatocyte toxic effect of bile salts by decreasing their detergent action

Chronic liver disease and biliary cirrhosis

Cat & dog @10-15mg/kg PO OD

Pregnant animal

Overdosage can cause diarrhoea

Tab golbi 150mg, 300mg and 450mg

Fluoruquinolene antibiotic

Inhibit the DNA gyrase enzyme

Skin, soft tissue infection, respiratory infections and urinary tract infections (especially in pet animals) 

• Cat-7. 5mg/kg/day
• Dog-2. 5-7.5mg/kg/day

Immature dogs during the rapid growth phase (between 2to8 month of age) - for small and medium size breed. Upto 18 month of age in large and giant breed. 

• Vomiting, diarrhoea, lack of appetite
• Cartilage abnormalities ( severe side effects) 
• Inordination seizures, trouble breathing, skin rashe. 

• Oral suspension-Orbax-20ml (30mg/ml) 
• Tab. Orbax-250 tabletstablets

Each tablet 22.7 mg

Fluoroquinolone antibiotics

• Inhibit the bacterial DNA gyrase enzyme and to poisomerase 4

Bacterial infections that cause bronchitis, pneumonia, chlamydia, gonorrhea, skin infection, urinary tract infections and infections of the prostate, conjunctivitis, corneal ulcer

Dog/Cat -Administer 1 drop to affected eye every 6hours, loading dose can be used 1 drop to affected eye every 15 minutes for 4 doses. 

Dog- 30mg/kg  , PO, OF

Calves/ Lamps/pig - 0.5ml/10kg of body weight, PO with drinking water

• Hypersensitivity
• Don't administer to animals with impaired renal function
• Don't use in pregnant dogs and cats. 
• Don't use to treat horses
• Don't administer to laying hens producing eggs for human consumption. 

• Eyepain, redness, itching, blurry vision and a bad taste in the mouth. 
• Inappetance, diarrhoea, hairloss

Inj oflokind oz (VET MANKIND) - 60 ml vials (Each 5 ml contains 50mg ofloxacin + 125mg ornidazole)

• Oflox eye oint-5g
• Oflox eye drops
• Oflox-D eye drops-10 ml
• Oflokind-Oz pet -90ml     

Ofloxacin and ornidazole (Oforf bolus 3.5g)

• Powder - Ofloxacare -2%
• Inj. Ty-Oflox-4- 100 ml

Non elective Beta adrenergic agonist

Act by binding with specific receptors  ( adrenergic beta 1 and beta 2) 

• Acute bronchial constriction,  cardiac arrhythmias (AV block) 
• Adjunctive therapy in shock or heart failure

Small animals: 10mcg/kg 6 hrs  iM  SC

• Patients with tachycardia, AV block caused by cardiac glycoside intoxication
• Ventricular arrhythmias, coronary insufficiency, hyperthyroidism, renal disease, TBP, diabetes

• Tachycardia
• Anxiety
• Tremors
• Excitability
• Headache
• Vomiting

Direct acting Arterial and venous dialators

Nitroprusside metabolised into nitric oxide

Nitric oxide stimulate cGMP pathway producing relaxation of vascular muscles

• Hypertension
• Acute heart failure secondary to mitral regurgitation
• Refractory CHF
• In DCM with dopamine/dobulamine

Small animals: 1-5 mcg/kg/min  IV (Maximum 10mcg/kg/min) 

Patients with

• Compensatory hypertension
• Hepatic insufficiency
• Renal impairment
• Geriatric patients

• Rapid hypertension
• Irritant at infusion site
• Chronic use leads to thiocynate and cyanide toxicity

Prusid-5ml (50mg/5ml) 

Antibiotics (broad spectrum aminoglycoside) 

• Bactericidal
• Bind with 30s (stronger binded) & 50s subunit of ribosomes    a)  Interferes with formation of initiation complex of protein synthesis          OR       Inhibits protein synthesis

• Tropical preparations for skin, eyes, ears
• Oral treatment: Treatment of enteric infection and to sterile colon prior to surgery
• Orally/enema: To decrease NH3 producing bacteria in hepatic encephalopathy. 
• Antibacterial spectrum: G -ve aerobic, several G +ve     Resistance:  pseudomonas,  strepto Pyogenes

• Ruminants: 3-6 mg/kg   6-12 hours interval   PO  88 mg/kg   8 hrs interval   SC
• Horse: 2-6 mg /kg    6-12 hrs interval     PO                     4.4 mg/kg     8-12 hrs interval  IV
• Small animals: 10-20 mg/kg      6-12 hrs interval      PO

• Not safe in neonates
• Chronic use leads to superinfection
• Not safe in neuromuscular disorder, renal problems
• Horse: antibiotics associated diarrhea (enterocolitis) 

• Parentral: nephrotoxic
• Orally: ototoxicity, Nephrotoxicity, severe diarrhea, intestinal malabsorption

Spray aluspray - awd (VETOQUINOL) - 125 ml

• Inj. Neospa (140 mg/ml)   30 ml vial
• Inj. Omycin vet (140 mg/ml)   30 ml vial
• Pow. Nubiotic-SP (20% W/W)  - 50g                               Pow. Unimycin  50% - 20g
• Oint. Neosporin  5g, oint. Neosporin-H  5g, oint. Nebasulf 15g, oint vetbacin 20g

Opiod antagonist

Binding to nul, kappa, sigma opiod receptors

Reversing agent of opiod analgesia/intoxication with opiods

• Horse: 0.01-0.05 mg/kg  IV
• Small animals: 0.01-0.04 mg/kg   IM, IV, SC

• Patients with cardiac abnormalities or opiod dependent. 
• Elevate BP in endotoxic or Hypocolemic shock, strokes, spinal surgery

High margin of safety  (in usual dose) 

NA

Topical application

 It Works By Killing Sensitive Fungi By Interfering With The Formation Of The Fungal Cell Membrane And Weakening It.

• Absrasions
• Cuts
• Wounds
• FMD lesions
• Post shearing lesions
• Surgical wound dressing
• Udder impetigo

Apply topically after proper cleaning of the affected area of wound for 3-4 times a aday

Kiskin (INTAS)

• 20g, 50gm tube
• Composition-
  Clobetasol propionate 0.03% w/w
  Ofloxacin 0.1% w/w
  Miconazole nitrate 2.0% w/w
  Zinc Sulphate 3.0% w/w

Infusions

NA

• Instant replenishment of fluid
• Electrolytes and energy in conditions associated with diarrhoea
• Heat stress and debility

Cattle, Buffalo and Horse @ 500-2000 ml

Sheep and Goat @ 100-200 ml

Calf @ 100-500 ml

Dog @ 25-100

(Dose can be differ as per degree of dehydration)

IV route

intalyte (INTAS)

• 500 and 1000ml FFS Sachets
• Each 100ml contains 

Dextrose(Anhydrous) 20 gm
Sodium Chloride 0.6 gm
Potassium Chloride 0.04 gm
Calcium Chloride(dehydrate) 0.027 gm
Sodium lactate 0.312 gm