Cefalosporin

Interfere with bacterial cell wall synthesis by inactivating transpeptidase enzyme

Bacreriacidal

Urinary tract infection

Respiratory tract infection

Localised infection

Cat and dog @ 10-30 mg/kg TID

Penicillin hypersensitive animals

In penicillin hypersensitive animals cause cross resistance 

Eliminate 

Tab 125mg and 250 mg

Syrup 30 ml (125 mg/ml) and 30 ml (250mg/ml)

Cefadrox

Tab 250 mg

Syrup 30 ml(125mg/5ml)

First generation cefalosporins

Interfere with bacterial cell wall synthesis by inactivating transpeptidase enzyme 

Bactricidal 

Respiratory tract infection

Urinary tract infection

Mixed infections

Localized infections

Cat and dog @10-30 mg/kg TID

Cattle and buffalo @ 5-10 mg/kg BID

Penicillin hypersensitive animals

In penicillin hypersensitive animals cause cross resistance 

Suspension lixen IU (VIRBAC) - 4gm 

Tab lixen (VIRBAC) - 1.5gm

Powder lixen (VIRBAC) - 20gm and 300 gm (75mg/gm)

Ceflax

• Prophylactic 20g/day/300 chicks
• Therapeutic 20g/day 1500 chick, 20/day 250 broilers, 20g/day 100 layers

Cephalex 

• Prophylactic 20g/day/300 chicks
• Therapeutic 20g/day 1500 chick, 20/day 250 broilers, 20g/day 100 layers

Cephast 

Powder 7.5%w/w

Antibiotic 

Inhibit bacterial wall synthesis

UTI

Soft tissue infection 

Calf scour

Otitis

Pneumonia

Cat and dog @ 7mg/kg IM parenteral and 6.6-20mg/kg PO

Cattles and horses @ 6.6-22mg/kg PO

Calves @ 10-22mg/kg PO

Hypersensitive animals 

Vomiting and diarrhoea 

AMOXICILLIN + CLOXACILLIN (Intamox) - (INTAS) 

• Inj 2.5gm, 3.5gm and 4.5gm vial (Dose in cat & dog @ 15-25mg/kg bwt daily for 3-5days IM IV)
• Cattle & buffalo @ 6-10mg/kg bwt

Bolus Intamox-O 

• 1.5gm (1bolus/200kg bwt orally daily for 3-5days) (INTAS)

 Amoxirum forte (VIRBAC)

• 300mg (200mg amoxycillin + 100mg Sulbactam )
• 3gm vials ( 2000mg amoxycillin + 1000mg Sulbactam )
• 4.5gm vials ( 3000mg amoxycillin + 1500mg sulbactam )

Tab amoxirum (VIRBAC)

• 1.5g 
• 2 tab and 6 tab packet
• 1.5g amoxicillin trihydrate per tablets

inj moxel (ALEMBIC) 

• 3000 mg vials
• each vials contains 1500 mg amoxicillin + 1500 mg Cloxacillin 

Cap Novamox, C aristomox - 250mg and 500mg

Syrup aristomox, Syrup novamox - 125mg/5ml

Antibiotic

Inhibits bacterial cell wall synthesis

Shipping fever, erysipelas, strangles

Cattle- 20, 000 IU/kg

Horse -20, 000-25, 000 IU/kg

Diarrhoea

Nausea, pain, vomiting

Antibiotic

Interfere with bacterial cell wall synthesis without affecting protein synthesis within the cells

Actinomycosis, Black leg, Tetanus, Arthritis, Mastitis, Tetanus and wound infection

Dogs and cats

40000 - 50000 units / kg IM repeat after 5 days

Cattle 

10000 - 60000 units /kg SC or IM repeat after 2 or 3 days

Horses

50000 units /Kg IM repeat after 2to 3 days

Swine

10000 - 40000 units/Kg IM every 3 days

Birds

100mg/Kg IM once daily

Penicillin hypersenstivity patients

Deep intramuscular administration only

Hypersenstivity, GI disturbances, Platelet dysfunction, Organ toxicity, Cation toxicity

Pencom 12 Inj 12 Lakh IU

Antibiotic

Interfere with bacterial cell wall synthesis

Cattle, sheep-shipping fever by Pasturella multocida 

Swine- Erysipelas

Horse- strangles 

Give 6000 IU per kg increase dose to 12,000 - 18,000 IU /kg for serious infection

Diarrhoea, methaemoglobenemia, anemia

Nausea, pain, vomiting

Antiviral drug

• It inhibits enzyme neuraminidase which helps in viral replication and passage of virus into new cell through the mucus membrane. 
• It reduces the entry of parvo virus into the mucosa of the intestine. 

Parvo virus infection in dogs. 

Equine influenza A in horse. 

• Dog  -   CPVE-2. 2mg/kg  PO, BD for 5days
• Horse- Equine influenza-2mg/kg PO, BD for 5 days

Hypersensitivity patients

Nausea and vomiting

Susp. Antiflu - 12 mg/ml

Cap Antiflu  - 75 mg

Antiviral Drugs

Inhibits viral replication ( viral DNA polymerase) depends on viral thymidine kinase for phosphorylation. 

Ocular Feline Herpes virus (FHV-1) 

Cats - q4 - 6h  small amount to affected eye (max -3 weeks) 

Ocular irritation

Hepatic dysfunction, Myelosuppression ,        CNS effects - convulsions,  coma, Fever, Phlebitis. 

Simplovir eye gel - 5g

Natclovir -  250 mg capsule

Virson gel -  5g

Natelovir -  500 mg tab

Gancigel eye ointment- 5 g

Clygan gel 1.5g

Anti viral drug - Purine analogue 

Synthetic guanosine nucleoside analogue substitute guanosine in DNA synthesis and inhibits viral replication

• Herpes viral infection

Birds @ 80 mg/kg PO 3 times daily

Horse @ 10 mg/kg Slow IV 2 times daily

Dogs and Cats @ 3mg/kg PO 5 times daily for 10 days and upto 10 mg/kg PO 5 times daily for next 10 days

10-20 mg/kg slow IV infusion 3 times daily

• Renal impairment
• Dehydration 
• Hypersensitive patient

Oral - GI disturbance

IV - Renal insufficiency in dehydrated state

Topical - Local irritation

Tab Herperax 400 mg

Tab Zovir 200 mg

Cream Acivir 5%

Gel Cyclovir 5 % 

Antitussive

• Non competitive NMDA receptor antagonist
• Nicotinic cholinergic receptor antagonist
• Raise threshold of cough centre

• Cough suppression
• Chronic bronchitis

• Dog/Cat= 1-2mg/kg PO or T/D
• Cattle= 5-15mg/kg

• Pneumonia
• Lung disorder

• Slowed breathing
• Blurred vision
• Drowsiness

Tab. DMR 20 - 20mg