Bronchodilator

Inhibition of Phosphodiesterase enzyme

Treat coughs caused by bronchospasm (Or) Bronchoconstriction

Cat - 4 mg/kg BID

Hypocalcemia

Persistent  vomiting, increase in urine volume

DERIPHYLLIN Theophylline 50.6mg +etophylline 169.4 mg/2ml

DERIPHYLLIN Tab 100 mg (etophylline 77 mg+ Theophylline 23 mg) 

Bronchodilator

Act on Beta2 adreno receptor affecting Bronchoconstriction

Treat bronchial asthma in cats

Dog - 0.05-0.1 mg/kg bwt TID PO

Horse - 0.0033 mg/kg bwt  IV                     0.025 mg/kg bwt PO

In pregnancy and lactation

Produce tremors, increased heart rate, dizziness and excitement

Tab bricanyl 2.5mg and 5mg

Syrup ascoril 200ml

Bronchodilator

• H1 receptor antagonist
• Antimuscarinic effect on vestibular apparatus 

• Allergy
• Rashes
• Pruritis 
• Anxiolytic
• Antiemetic 

Ruminant=0.5-1mg/kg q 6-8hrs I/M or I/V

Dog and cat= 1-2mg/kg PO

• Hypertension
• Hepatic disorder
• Increase intraocular pressure
• Pregnancy

• Dry mouth
• Dizziness
• Nausea
• Increase chest congestion

• Tab. Benadryl AH 25mg capsule
• Tab. Hydramin 25mg capsule
• V Cofex Syrup 500ml, 1L and 5L

Bronchodilator

Inhibition of phosphodiesterase (PPE 1 & PPE 2)enzymes

• CHF
• Bronchitis
• Emphysema
• COPD

• Dog=6-10mg/kg I/V or PO
• Cat=4-6mg/kg I/V or PO

• Pregnancy hypocalcaemia
• Hepatic disorder

• Nausea
• Vomiting
• Headache

Deriphyllin  - 2ml

Bronchodilators 

Potent inhibitors of phosphorus enzyme and increase cAMP

Feline bronchial asthma

Cats @ 6.6mg/kg PO BID and 2-4mg/kg slow IV

dogs @ 9-11mg/kg TID/qid

NA

Excitement and hypocalcaemia

Tab 100mg

Inj 250mg/10ml

Fluoroquinolone

Inhibits supercoiling of DNA in the bacteria, producing bactricidal action.

Respiratory tract and urinary tract infection in cats and dogs

Glasser’s disease in horse

Infectious Cory a, colisepticemia, CRD, salmonellosis, fowl cholera

Cat & dog @ 5-15mg/kg PO IM IV

Cattle & sheep @ 4-5mg/kg PO IV IM

In Young ones cause arthropathic effects

GI disturbances 

CNS disturbances and rashes

C-flox TZ - Bol 3.3gm and Tab 550mg (Dose @ Large animals 1-2 Bol OD for 3-5 days and in small animal 1tab/15-25 kg bw) (INTAS)

INJ. C-flex TZ IU - 60ml bottle (125mg Ciprofloxacin + 150mg tinidazole / 5ml) (INTAS)

Ceflox-Tz vet - Bol 3.3G and Susp 60ml 

Ciptas -L - Tab 250 mg ((In small animal 0.5-1 tab /20-25 kg bw BID for 3-4 days)

Griptol - Susp 60ml (In small animal 5ml/20-25kg BW BID for 3-4 days)

Antibiotics

A bacteriostatic Macrolides antibiotic binds to 50s ribosomal subunit suppressing bacterial protein synthesis

Against mycoplasma

Dogs -10 to20 mg/kg PO q 12 hrs,

cattle - 18 mg/kg IM q 24 hrs,

Goat - 10 mg/kg (do not exceed more than 5 days) ,

Birds - upper respiratory tract infection 10 -40 mg/kg IM, BID Or TID ,

elephant - 12 mg/kg OD for 5 days ( Mycoplasama infection)       

POWDER FORM                        Dogs- 1/16 th of teaspoon 2-3 times daily for dogs less than 7 kg, (greater than 7 - 15kg ) - 1/8 th of teaspoon  2-3 times a dog for medium dogs 1/4 teaspoon 2-3 times a day for larger dogs( greater than 15 kg) 

Don not give to guinea pigs, hamster, rabbits

• Gastro intestinal upset         pain and inflammation at injection site                             decreased appetite, diarrhoea

Trox powder (VIRBAC) - 120g (50%w/w)

powder TYLO 62.5,100g       

inj. Tylan 200,250ml

Macrolytic antibiotic
prokaryotic drug

Bind to 50s sub unit of bacterial ribosome and prevent growth of bacteria by interfering with protein synthesis

Only in foal below 1 year not above Respiratory tract infection
Genital tract
Skin and soft tissue
Against intracellular organism

Cattle @
As prokinetic @ 1.1 to 8.8 mg/kg IV Single dose in leucocytes

Cat @ 5mg/kg PO Once daily

Dog @ 5-10(upto 40)mg/kg PO Once daily

Foals @ 10 mg/kg PO Once daily (initially) followed by alternate days

Hypersensitive patient
Liver disfunction
Horse above 1 year fetal digestive disturbance

G.I disturbance
Very rarely nervousness dermatological reactions

Inj Azee 500mg (Each ml of reconstituted injection contains 100 mg)

Suspension Azee 100mg/ml

Tab Azee 250mg, 500mg, 1000 mg

Powder Azithral P 100g, 1000g

Marcrolid antibiotics

Like other macrolid antibiotics bind with 50s ribosomal subunit and cessation of bacterial protein synthesis

Cat @ 10-15 g/kg PO

dog @ 10-40g/kg PO

cattle, sheep, goat,horse @ 2.2-4.4 g/kg bw PO

Allergies from other macrolids like Azithromicin

• do not combine with digoxin

Nausea, vomiting, diarrhoea, stomach pain, loss of appetite

Althrocin - Tab 250 and 500mg and Liq 60 ml (125g/5ml)

Anithrocin FS. - Powder 1g

Erycin - Tab 125 mg, 250 mg, 500mg