Third generation cephalosporin.

Interfere with bacterial wall synthesis by inactivating transpeptidase enzyme

Bactricidal

Intra abdominal infections

Respiratory tract infections

Localized infection

Urinary tract infection

Cat & dog @ 10mg/kg BID

Penicillin hypersensitive animals

Be cautious in penicillin hypersensitive animals 

Cefix

Tab 100mg and 200 mg

Cefspan 

Suspension 30ml (100mg/5ml)

Ceftas

Tab 100, 200, 400mg

Selective prolactin inhibitors

Dopamine receptor agonist

Ergot derivative 

Reduce the amount of prolactin from pituitary gland

Induction oestrus

pseudopregnancy in bitches

induce abortion in queens and bitches

pituitary adenoma in rats

For pseudopregnancy@ 5mcg/kg PO for 5-10 days

For pregnancy termination @ 5mcg/kg PO for 5 days (at 30 days in cats and after 40 days in dog)

for oestrus detection @ 5mcg/kg PO OD induces fertile pro oestrus in 4-25 days and administer until onset of oestrus.

Cause abortion 

dopamine antagonist will counteract effect

anti hypertensive drugs will cause hypotension 

Cabgolin - Tab 0.25mg, 0.5mg

Colette - Tab 0.5mg

Expectorant

Mucolytic action by distrupting the structure of acid mucopolysaccharide fibres in mucoid sputum and produces viscous mucus

Promotes secretion of sputum liquifying mucus

Done by breaking acid polysaccharide fibrous structure present in sputum

Respiratory distress, Cough due to pneumonia and bronchitis

Cattle, Sheep and Goat

0.2 to 0.5 mg /Kg BW, OD, PO or IM

Dogs

1.6 to 2.4 mg /Kg BID PO

3-15 mg/ dog IM PO BID

Cats

1mg /Kg BW OD PO

3mg/ Cat IM OD

Horse

0.1 to 0.25 mg /Kg OD, IM, PO

Birds

1.5mg/Kg  BID IM, PO, OD

Hypersenstivity or idiosyncratic reaction to bromhexine

Rhinorrhoea 

Lacrimation

Bromhexime Tab 5mg

Syrup 3mg/5ml

Antibiotic 

Beta lactamase resistant

Otitis

UTIs

Wound infection 

Respiratory infections 

Cats and dog @ 8.75 mg/kg IV and 12.5-25 mg/kg PO

Horses @ 15-25mg/kg IV

Hypersensitive animals 

Diarrhoea 

Tab augmentin 375mg, 625 mg

Tab Apcil 375mg and 625 mg

Dry syrup augmentin 125mg/5ml

Tab moxclav 375mg and 625 mg

Anti biotic

Aminiglycosides that inhibit bacterial protein synthes

Septicemia, UTI, burns, post operative care

Cats @ 10-15mg/kg IV IM SC q24hr

dogs @ 15-30mg/kg IV IM SC q24hr

Cattle @ 10mg/kg in adult and 20mg/kg in calf IV IM SC q24hr

Horses @ 4.4-6.6mg/kg in adult and 20-25mg/kg in foal IV IM q12hr

Renal dysfunction 

Contraindicated in dehydrated and pregnant animals also

Inj Amikacin sulphate 500mg/2ml 

Suspension tamik 50ml

Antacids

Neutralize gastric HCl

Bind to phosphate in GI tract and making it unavailable for absorption 

Bind to pepsin and stimulate local PGE1 

Gastritis, gastric ulcers, hyperphosphatemia in cats and dogs

Cats and dogs @ 10-20mg/kg PO q6-8hr

0.5-1ml/kg PO q6-8hr after meal

prior administration of digoxin

Constipation 

Alucap, gelucil, acidex, mg salt (asilone, maolax, mucogel)

Cholagogues and cholerectic agent

It increases bile flow

Also decrease intestinal absorption of cholesterol

It reduces the hepatocyte toxic effect of bile salts by decreasing their detergent action

Chronic liver disease and biliary cirrhosis

Cat & dog @10-15mg/kg PO OD

Pregnant animal

Overdosage can cause diarrhoea

Tab golbi 150mg, 300mg and 450mg

Fluoruquinolene antibiotic

Inhibit the DNA gyrase enzyme

Skin, soft tissue infection, respiratory infections and urinary tract infections (especially in pet animals) 

• Cat-7. 5mg/kg/day
• Dog-2. 5-7.5mg/kg/day

Immature dogs during the rapid growth phase (between 2to8 month of age) - for small and medium size breed. Upto 18 month of age in large and giant breed. 

• Vomiting, diarrhoea, lack of appetite
• Cartilage abnormalities ( severe side effects) 
• Inordination seizures, trouble breathing, skin rashe. 

• Oral suspension-Orbax-20ml (30mg/ml) 
• Tab. Orbax-250 tabletstablets

Each tablet 22.7 mg

Fluoroquinolone antibiotics

• Inhibit the bacterial DNA gyrase enzyme and to poisomerase 4

Bacterial infections that cause bronchitis, pneumonia, chlamydia, gonorrhea, skin infection, urinary tract infections and infections of the prostate, conjunctivitis, corneal ulcer

Dog/Cat -Administer 1 drop to affected eye every 6hours, loading dose can be used 1 drop to affected eye every 15 minutes for 4 doses. 

Dog- 30mg/kg  , PO, OF

Calves/ Lamps/pig - 0.5ml/10kg of body weight, PO with drinking water

• Hypersensitivity
• Don't administer to animals with impaired renal function
• Don't use in pregnant dogs and cats. 
• Don't use to treat horses
• Don't administer to laying hens producing eggs for human consumption. 

• Eyepain, redness, itching, blurry vision and a bad taste in the mouth. 
• Inappetance, diarrhoea, hairloss

Inj oflokind oz (VET MANKIND) - 60 ml vials (Each 5 ml contains 50mg ofloxacin + 125mg ornidazole)

• Oflox eye oint-5g
• Oflox eye drops
• Oflox-D eye drops-10 ml
• Oflokind-Oz pet -90ml     

Ofloxacin and ornidazole (Oforf bolus 3.5g)

• Powder - Ofloxacare -2%
• Inj. Ty-Oflox-4- 100 ml

Non elective Beta adrenergic agonist

Act by binding with specific receptors  ( adrenergic beta 1 and beta 2) 

• Acute bronchial constriction,  cardiac arrhythmias (AV block) 
• Adjunctive therapy in shock or heart failure

Small animals: 10mcg/kg 6 hrs  iM  SC

• Patients with tachycardia, AV block caused by cardiac glycoside intoxication
• Ventricular arrhythmias, coronary insufficiency, hyperthyroidism, renal disease, TBP, diabetes

• Tachycardia
• Anxiety
• Tremors
• Excitability
• Headache
• Vomiting