• To treat Mastitis (subclinical mastitis)
• Adjunct to antibiotic therapy in clinical mastitis

Milk pH buffer - Act as milk pH buffer and normalize the  milk pH from alkaline to normal i.e., 6.5. This makes the milk unfavourable for microbial growth and free from bacterial contamination.

Immunopotentiator - Mammidium improves the cellular immunity against mastitis, therapy protects mastitis affected tissues

Antioxidant effect - Mammidium enhances cellular antioxidant level, which reduces cellular oxidation and prevents mastitis

• Sub-clinical mastitis
• Adjunct to antibiotic therapy in clinical mastitis

50 g powder for 4 consecutive days as an Electuary by mixing with jaggery

NA

NA

Amber coloured glass bottle containing 50 g powder

Synthetic polycyclic steroids

• Preferential inhibition of 5-alpha-reductase (Type II) enzyme
• This enzyme converts testosterone into dihydrotestosterone that cause enlargement of prostate

Benign prostatic hypertrophy

Reduce prostate size without affecting semen quality and testosterone production 

Dog-0. 1-0.5 mg/kg OD PO  

Used only in males not female

In breeding animals, it can get secreted into semen, can cause fetal abnormalities.

Tablet finalo (1mg) 

Tablet fincar (5mg) 

Sedative

Alpha-2 adreno receptor agonist

Sedative , analgesic, muscle relaxant, blood pressure maintenance.

Cattle-22to 50 µg/ KG
Pig - 80 micro gram per Kg

dog -

1.pre-Anastasia 10 to   20 micro gram per KG

2.slight session 10 to 30 micro gram per KG

3.moderate to dip station 30 to 80 micro gram per KG

cat-

1.moderate sedation- 50-100 µg/ KG,

2 Deep sedation 100 - 1 50 µg/ KG.

Pregnancy animal

Pregnancy toxaemia

Domitor(1mg/ml) —10ml

Livmedet(40mg/ml)—20ml

Sedative

Inhibitory neurotransmitter in CNS

• Muscle relaxant
• Control of seizure
• Anaesthetic

• Ruminant=0.6-1.1 mg/kg
• Horse - 0.05-2mg/kg IV 

Dog=preanesthetic - 0.2-0.5mg/kg IV.

•  Muscle relaxant -2-10 mg/kg PO.                                         

Seizure management - 0.5-1 mg/kg IV     

Cat=Anxiolytic:0.2-0.4 mg/kg PO.                                   

• Appetite stimulant : 0.5-1 mg/kg IV.                                     
• Muscle relaxant : 1.25-5 mg/kg PO

• Thrombophlebitis
• CNS excitement in drugs

Depression in cats

• Tab. Valium 5mg,10mg
• Injection Dizapam 2ml
• Tab Calmpose 2mg, 5mg, 10mg
• Inj Calmpose 2ml (5mg/ml)

Antacid

Neutralise the gastric acid HCL

Rumen acidosis, grain overload, Rumen impaction

Cattle - 1g/kg .

sheep, goat ,calf - 200-300mg/kg.

dog -5 to 10 ml.

cat-5 to 15 ml(BID)

Horse - 15ml(QID)

Renal disease.

Alkalosis.

Syrup: Bloatarid -100ml

              Helico PH

Pro kinetic drugs

Gastro intestinal prokinetic agents

Feline idiopathic mega colon and GI stasis in rabbit.

Cats @ 0.1-1 mg/kg q8-12hr

Small mammals @ 0.1-1 mg/kg q8-12hr

Within 2hr of metoclopramide and ranitidine 

Abdominal cramps and diarrhoea

Tab Alipride / Cisade - Tab 10 mg

Ciza - Tab 5mg and 10 mg , suspension 1mg/ml (Banned)

Anti emetic,  pro kinetic 

Central D2 receptor antagonism

5HT3 Antagonism - Higher dose

At Antiemetic chemoreceptor trigger zone.

GI prokinetic effect

-local D2 antagonism

-Stimulation of muscarinic Ach and 5HT4 receptors.

Vomiting, Desophagitis,Emptying stomach prior to induction of general anaesthesia. 

Dog, cat - 1 to 2 mg/kg - (IV).

Birds-(0.3-2mg/kg) - IM

Pig - 0.5 - 1mg/ kg - (SC)

GI obstruction, perforation, epileptic patients,

Drug Interaction: Inhibited by Anti muscarinic drugs, and narcotic analgesics.

Tablets

Periorm-5,10mg

Injection 

Perinorm-2 ml(5mg/ml).

Syrup 

Perinorm- 30 ml ( 5mg/5ml).

Progesterone preparation

• Maintains the endometrium and is important for the continuity of pregnancy
• Promotes mucus formation in vagina, participates in development of alveolar system in mammary gland
• At low dose, cause ovulation

• Habitual / threatened abortions due to inadequate progesterone level
• Uterine prolapse
• Repeat breeding due to failure of embryo implantation as a result of luteal insufficiency

Route - IM

Habitual abortion indications in Early pregnancy - 3ml IM after 45 days of pregnancy and to be repeated 4-5 times at every 10 days interval

Habitual / threatened abortions ( mid / late pregnancy ) - 3ml IM for 3 days and followed by weekly injection for next 3 weeks

Uterine prolapse (due to pronounced heat) - 3 ml IM to be repeated on 3rd day, if required

Post partum uterine prolapse - 3 ml IM at every alternate day, followed by weekly injection for 3 weeks

Anti partum uterine prolapse - 3 ml IM at 2 days interval for 3 times

Repeat breeeders (with luteal insufficiency) - 2-3 ml IM at 5th, 12th and 19th days post Al .

• Prolonged exogenous administration - Uterine glandular hyperplasia, uterine fluid accumulation, endometritis
• Pregnant animal

• Pain at site of administration
• Allergic skin rashes
• Urticaria may be encountered

Inj. PROGESYN (INTAS)

• 3 ml ampoule
• Each ml contains

Hydroxyprogesterone caproate IP........0.25g
Benzyl alcohol IP........0.02ml (as preservative)

Inj. P Depot (ZYDUS)

• 2ml, 3ml ampoules
• 250mg/ml

inj duraprogen (VETCARE)

• 2ml ampoules
• 0.25gm/ml

inj gestabliss (VET MANKIND)

• 0.25gm /ml

Phosphorous binders

Control high blood levels of phosphorous in CKD

CKD

Cat @ 200mg 2-3 times daily

Dog @ 400mg PO with meals

Hypophosphatemia or bowel obstruction

Hypersensitive

Reduced apetite

Vomitting

Constipation or Diarrhoea

Tab. Sevalmer HCl 400mg and 800mg

Tab. Sevalmer carbonate 800mg

Tab. Acutrol 800mg

Renagel

Hormone

Direct luteolytic action

• Terminate pregnancy
• Estrous synchronisation
• Induction of parturition 
• Pyometra

Cattle:

•     Abortion= 25mg total dose once I/M
•     Synchronisation= 25mg I/M for 10-20 days
•     Pyometra = 25mg

Dog:

• Abortion= 0.025-0.05 mg/kg q 12hrs I/M
• Pyometra= 0.1-0.2 mg/kg S/C

Hepatic, renal, systemic disease in pregnancy except MTP

• Decrease appetite
• Cramping
• Sweating

• Injection Lutalyse 5ml,10ml (5mg/ml)
• Injection Pro Dino 5mg/ml