Anti helmintics

Inhibit polymerization of tubulin in parasi to and blocks the glucose uptake

Trematodal infections, especially fasciola species

Cattle, Buffalo -12 mg/kg

Sheep, goat - 10 mg/kg

Hypersensitivity

Skin irritation

Suspension triclamar (VIRBAC)

• 100ml and 500ml bottle 
• each 5ml contains 250 mg triclabendazole + 5mg ivermectin 

Olgardsolution 250 ml, 500ml, 1L                                    TRICLASOLE, FASINE           BOLUS- 900mg                        suspension - 100ml, 500ml, 1 litre  (50mg/ml) 

Endo-ectoparasiticide 

Enhance release of GABA at presynaptic neurons resulting in paralysis of parasites and death

• Nematode, lice, mite, tick infestations
• Preventive for heart warm in dogs

• Ectoparasite: 0.2-3 mg/kg SC   PO
• Endoparasite: 0.2-0.4 mg/kg  SC  PO weekly
• Demodex: 0.6 mg/kg SC   PO daily

• Foals less than 4 months old, puppies less than 6 weeks old
• Collie type breeds and shelties, Australian Shepherds

• Hypersensitivity reactions
• Neurotoxicity
• Induce serious effects by killing the larva when they are in vital areas

Inj. Neomec (INTAS)

• 1 ml, 10ml and 100ml vials
•  Each ml contains 10 mg

Inj. Neomec sx (INTAS)

• 10ml vials
•  Each ml contains 10 mg ivermectin + 100 mg clorsulon

Inj. Neomec LA (INTAS)

• 10ml vials
•  Each ml contains 31.5 mg ivermectin + 0.18% w/v methyl paraben + 0.02% w/v propyl paraben

Inj Endact LA (VETOQUINOL)

• 10 ml vials
• 31.5mg/ml
• S/C route
• 1ml for 50 kg bwt

Inj Endact Plus (VETOQUINOL)

• 10 ml vials
• Ivermectin 1%w/v + clorsulon 10%w/v per ml
• S/C route
• 1ml for 50 kg bwt

Inj hitek (VIRBAC) 

• 10ml, 30ml and 100ml vials
• Each ml contains 10 mg

Inj hitek F (VIRBAC) 

• 10ml vials
• Each ml contains 10 mg ivermectin + 100 mg clorsulon

Inj hitek platinum (VIRBAC) 

• 10ml vials
• Each ml contains 31.5 mg

Solution hitek (VIRBAC) 

• 100ml, 500ml, 1L and 2 L bottle 
• Each ml contains 0.8 mg

Tab hitek (VIRBAC) - 80 mg

bolus fendikind plus (VET MANKIND) - (3 gm fenbendazole + 100 mg ivermectin/ bolus)

Inj

• Mectin- 1 ml, 7ml, 10 ml, 20 ml -- (10mg/ml) 
• Avertin, endicitin

Oral solutions

• Neomec- 100ml, 500ml, 1L -- (0.08% W/V) 
• Hitek- 100ml, 500ml, 1L -- (0.08% W/V) 
• Iverix, endicitin (0.1%W/V), (0.8%) 

Tablet

• Neomec 10mg
• I-meet 20mg
• Ivertin 10mg

Bol

• Hitek 80mg

Pouron

• Hitek 50 ml (0.5% W/V)

Powder

• Hitek 100g, 200g, 1kg (1% W/V) 

Anhelmintic

Depolarization neuromuscular blocking agents,

In Hemonchus spp - Inhits fumarate reductase.

Hemonchus spp, Ostertagia spp, Trichostrongylus spp,Nematodirus spp, ,cooperia spp, Oesophagestomum radiatum.

Cattle- 9.68 mg / kg PO

Sheep and goat - 10 mg / kg -PO.

Nil

NA

Oral solution banminth 100ml

Bolus banminth 594mg

Tab banminth 118.8mg

Antihelminthic drug

Cesticide action, increases the cell membrane permeability of worms resulting in loss of intracellular Ca+ and causes paralysis thus the parasites are phagocytised and digested

Treatment of pipylidiam caminum / taenia, ecchinacea, used in pets travel scheme to UK

Dogs- 5.0 mg/kg PO 5 mg/ kg spot on, 

Cats - 5 mg/ kg b. Wt

Elephant- 2.5-4 mg/ kg 

Do not use in young puppies/ kitten as they are susceptible to tapeworms, don't use spot on for animals having 1 kg body wt. 

Injection may cause localized sensitivity to tissue especially in cats, can cause transient hypersalivation if cat lick area where spoton applied, oral administration may cause anorexia, vomition, lethargy and diarrhoea

Drontal plus from 2 weeks of age, Drontal cat tab. From 6 week age, spoton

Antihelminthic drug

Tetrahydropyrimidine inhibitor of acetyl choline

Against nematode

Dog - 5-10 mg/kg repeat  after  1 week (ancyclostoma species) 

Cat- 20-30 mg/kg repeat after 1 week

Cattle-6. 5-13mg/kg B. Wt

Renal problems, epilepsy, hepatic disorders

Nausea, diarrhoea, vomiting, stomach cramps

Tab Kiwoff cat, worm trap, nemocid

Tab prazisam plus (VETOQUINOL) - 30 x 2 tablets (each tablets contains praziquantel 50mg + pyrantel paomate 144mg + fenbendazole 500mg)

Suspension Worex

Syrup Nemocid

• 10 ml
• Each ml contains 50 mg

Anthelmintics

Inhibitors of ACh asterase

Nematodes and microfilaricidal

Cat and dog@ 7.5mg/kg for microfilaria and 2.5mg/kg as immunomodulant

Cattle @ 5.5-11mg PO

Sheep & goat @ 8mg/kg

Rabbit @ 12.5-20mg/kg PO

Hyper sensitivity patients

High dose cause immuno depressant

Bolus nilzan (VIRBAC) - 2 bolus per cattle/buffalo

suspension nilzan (VIRBAC) - 100ml and 500ml and 1000ml bottle 

Powder nilverm (VIRBAC) 10gm and 100 gm

Inj levamisole 2ml, 5ml (15mg/ml)

Tab decaf is 150mg

Bolus amphicide 1.5gm

Liq nilzan 100ml, 150ml, 500ml

Syrup hexanide plus 90ml, 1L

Solution neozide plus 90ml, 500ml

Pro benzimidazole (anti helmintics) 

Blocking the microtubules, perturbs the uptake of glucose, which eventually empties the glycogen reserves, so whole energy metabolism blocked worms that are paralyzed and die or are expelled

roundworms, hookworm, whipworm in puppies

Dogs- orally 10-25 mg/kg/day

Cats- orally 10mg/kg

Cattle- orally 7.5-10mg/kg

Pregnant animal

In pregnant animals

Tab skyworm

Tab sky worm XL

Tab canworm

Tab Kiwof plus

Susp kiwof 

Tab endogard for canine

Tab cazitel plus for canine 

Anti helmintics drug

• Inhibits polymerization of tubulin in the parasite and block the glucose intake. 
• It interfere with enzyme fumarate reductasein energy production. So the energy production levels of the parasite deminishes and result in death. 

Removal of lungworm and roundworm in cattle effective against Nematodal, cestodal and trematodal infestation ( both larva and adult stage) 

• Dog- 10 mg/kg  PO, OD 28days
• Horse- 10mg/kg  PO repeat after 6-8 weeks
• Cattle- 4.5 mg/kg  PO repeat after 4-6 weeks
• Sheep-5 mg/kg PO
• GOAT- 7.5mg/kg  PO
• pig- 3-4.5 mg/kg PO

CI in emaciated horse and foals under 4 months of age

Loss of appetite, diarrhoea, fever, cramps, nausea, vomit, convulsions. 

• Bolus oxfendazole 2.2 g
• Bolus Oxfen care-150 mg
• Bolus wentril 2.5 g
• Bolus Axfendol 2.2 g
• Bolus  Oxfendo plus- Oxfrndozole & Ivermectin bolus vet. 

Antihelminth drug

GABA agonist, inhibition of Ach reversibility

Against ascarids

Dog- 100-200 mg/kg P/O (ascarids Parasites) 

Cat- 100-200mg/kg 

Cattle-110-300mg/kg 

Poultry-32 mg/kg 

Liver disease, impaired renal function, epilepsy administer orally at night no fluid after feeding

Joint pain, Vision blurring, 

Piperazine hexahydrate solution 300 mL, Ultraguard RID worm for cats, HARTZ-paste against round worm

Anthelmintic(benzimidazole)

Inhibiting polymerisation of tubulin in microtubules Of parasites - distrupts energy metabolism

Nematodal and cestodal infection 

Cattle , horse ,sheep ,goat , pig  - 10 - 15 mg/ kg PO 

Dog and cat - 22mg/ kg PO

Elephant - 2.5-7 mg /kg PO 

NA

NA

Tablet - Robendol - 500mg 

Tablet - mebex - 100 mg 

Tablet - Eben - 100mg 

Syrup - Eben - 100mg/5ml

Syrup- Mebex 30ml(100mg/5ml