Semi synthetic beta lactamase inhibitor

Irreversible inhibitor of beta lactamase 

Exerting its action by binding with these enzymes and blocks their destructive hydrolytic activity.

Mastitis, Pneumonia, Peritonitis, H.S.

Cat & dog @ 15-25mg/kg IV IM

Sheep and goat @ 10-15 mg/kg IV IM

Large animals @ 5-10mg/kg IV IM

Penicillin hypersensitive animals

Cause cross resistance in penicillin hypersensitive animals

Inj Wocef x ( VETOQUINOL)

• 3.375g and 4.5 gm vials

Inj Intacef tazo (INTAS)

• Inj 562.50 mg, 2250mg, 3375mg, 4500mg

Vetaceph tazo

Inj 3375 mg

Vetazo

Inj 2250 and 3375mg

Third generation cephalosporin 

Beta lactam antibiotic that produce bactericidal action by interfering with production of cell wall peptoglycan causing cell wall lysis.

Metritis

mastitis

pyometra

endometritis

nephritis

endometritis

osteo arthritis

HS

Small animal @ 15-25 mg/kg IM IV SC

Large animal @ 5-10 mg/kg IM IV SC

Penicillin hypersensitive animals

Cause cross resistance in penicillin hypersensitive animals

Wocef (VETOQUINOL) - 500mg, 3 gm and 4 gm vial

Axone - Inj 0.5g, 2gm, 3gm (CADILA)

 Cefcare - Inj 500mg

Cefstan - Inj 500mg and 3gm

 Cefzon - Inj 3gm

Cencef - Inj 3gm

Ciplacef - Inj 3gm

 Haxone - Inj 0.25, 0.5, 1, 2,3gm

 Intacef - Inj 0.25, 0.5, 1, 2,3,4gm (INTAS)

 Lyxaceft - Inj 3gm

Moxef - Inj 250mg, 2g, 3G

 Novicef - Inj 3gm

Safevet - 3G

 Seftrivet - Inj 3gm, 4gm

TT cef - Inj 0.5g and 3gm

 Tricef - Inj 3gm

 Vetaceph - Inj 1, 2 ,3 4gm

Third generation cephalosporin 

Binds to penicillin binding proteins which inhibit final transpeptidation and cause lysis of bacteria cell wall

Respiratory tract infection, Urinary tract infection, Localied infections, tuberculosis

Cat & dog @ 25-50 mg/kg IM IV (divided dose)

Penicillin hypersensitive animals

Cause cross resistance in penicillin hypersensitive animals

Britax

Inj 250mg, 500mg, 1g

Cefotaxime

Inj 250mg, 500mg, 1g

Crilcef

Inj 3gm

Haltax

Inj 2g

Lyfovet

Inj 2gm and 4gm

Taxim

Inj 125mg, 250mg, 500mg, 1gm, 2gm

Cefalosporin

Interfere with bacterial cell wall synthesis by inactivating transpeptidase enzyme

Bacreriacidal

Urinary tract infection

Respiratory tract infection

Localised infection

Cat and dog @ 10-30 mg/kg TID

Penicillin hypersensitive animals

In penicillin hypersensitive animals cause cross resistance 

Eliminate 

Tab 125mg and 250 mg

Syrup 30 ml (125 mg/ml) and 30 ml (250mg/ml)

Cefadrox

Tab 250 mg

Syrup 30 ml(125mg/5ml)

First generation cefalosporins

Interfere with bacterial cell wall synthesis by inactivating transpeptidase enzyme 

Bactricidal 

Respiratory tract infection

Urinary tract infection

Mixed infections

Localized infections

Cat and dog @10-30 mg/kg TID

Cattle and buffalo @ 5-10 mg/kg BID

Penicillin hypersensitive animals

In penicillin hypersensitive animals cause cross resistance 

Suspension lixen IU (VIRBAC) - 4gm 

Tab lixen (VIRBAC) - 1.5gm

Powder lixen (VIRBAC) - 20gm and 300 gm (75mg/gm)

Ceflax

• Prophylactic 20g/day/300 chicks
• Therapeutic 20g/day 1500 chick, 20/day 250 broilers, 20g/day 100 layers

Cephalex 

• Prophylactic 20g/day/300 chicks
• Therapeutic 20g/day 1500 chick, 20/day 250 broilers, 20g/day 100 layers

Cephast 

Powder 7.5%w/w

Antibiotic 

Inhibit bacterial wall synthesis

UTI

Soft tissue infection 

Calf scour

Otitis

Pneumonia

Cat and dog @ 7mg/kg IM parenteral and 6.6-20mg/kg PO

Cattles and horses @ 6.6-22mg/kg PO

Calves @ 10-22mg/kg PO

Hypersensitive animals 

Vomiting and diarrhoea 

AMOXICILLIN + CLOXACILLIN (Intamox) - (INTAS) 

• Inj 2.5gm, 3.5gm and 4.5gm vial (Dose in cat & dog @ 15-25mg/kg bwt daily for 3-5days IM IV)
• Cattle & buffalo @ 6-10mg/kg bwt

Bolus Intamox-O 

• 1.5gm (1bolus/200kg bwt orally daily for 3-5days) (INTAS)

 Amoxirum forte (VIRBAC)

• 300mg (200mg amoxycillin + 100mg Sulbactam )
• 3gm vials ( 2000mg amoxycillin + 1000mg Sulbactam )
• 4.5gm vials ( 3000mg amoxycillin + 1500mg sulbactam )

Tab amoxirum (VIRBAC)

• 1.5g 
• 2 tab and 6 tab packet
• 1.5g amoxicillin trihydrate per tablets

inj moxel (ALEMBIC) 

• 3000 mg vials
• each vials contains 1500 mg amoxicillin + 1500 mg Cloxacillin 

Cap Novamox, C aristomox - 250mg and 500mg

Syrup aristomox, Syrup novamox - 125mg/5ml

Antibiotic

Inhibits bacterial cell wall synthesis

Shipping fever, erysipelas, strangles

Cattle- 20, 000 IU/kg

Horse -20, 000-25, 000 IU/kg

Diarrhoea

Nausea, pain, vomiting

Antibiotic

Interfere with bacterial cell wall synthesis without affecting protein synthesis within the cells

Actinomycosis, Black leg, Tetanus, Arthritis, Mastitis, Tetanus and wound infection

Dogs and cats

40000 - 50000 units / kg IM repeat after 5 days

Cattle 

10000 - 60000 units /kg SC or IM repeat after 2 or 3 days

Horses

50000 units /Kg IM repeat after 2to 3 days

Swine

10000 - 40000 units/Kg IM every 3 days

Birds

100mg/Kg IM once daily

Penicillin hypersenstivity patients

Deep intramuscular administration only

Hypersenstivity, GI disturbances, Platelet dysfunction, Organ toxicity, Cation toxicity

Pencom 12 Inj 12 Lakh IU

Antibiotic

Interfere with bacterial cell wall synthesis

Cattle, sheep-shipping fever by Pasturella multocida 

Swine- Erysipelas

Horse- strangles 

Give 6000 IU per kg increase dose to 12,000 - 18,000 IU /kg for serious infection

Diarrhoea, methaemoglobenemia, anemia

Nausea, pain, vomiting

Antiviral drug

• It inhibits enzyme neuraminidase which helps in viral replication and passage of virus into new cell through the mucus membrane. 
• It reduces the entry of parvo virus into the mucosa of the intestine. 

Parvo virus infection in dogs. 

Equine influenza A in horse. 

• Dog  -   CPVE-2. 2mg/kg  PO, BD for 5days
• Horse- Equine influenza-2mg/kg PO, BD for 5 days

Hypersensitivity patients

Nausea and vomiting

Susp. Antiflu - 12 mg/ml

Cap Antiflu  - 75 mg